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Ampaiwan Chuansumrit
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Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

Education:
1. MD - Faculty of Medicine Siriraj Hospital, Mahidol University
1977
2. Diploma of the Board of Pediatrics of the Medical Council,
1983
Thailand
3. Diploma of the Board of Hematology of the Medical Council,
1985
Thailand
4. World Federation of Hemophilia trainee at Malmo General Hospital, 1986
Malmo, Sweden for 3 months
5. Research fellow for 1 year at University of Colorado Health
1986-1987
Science Center, Denver, Colorado, U.S.A.
6. Exchange scientist under JSPS grant, School of Medicine,
1989
St Marianna University and Nara Medical College Japan for 2 months
7. "Visiting Scholar" at Section of Molecular Genetics, Department of 1991-1998
Medicine & Pharmacology, Royal Hallamshire Hospital, University
of Sheffield, United Kingdom for 1-4 months/year for 4 years
Present Position:
1. Editorial Board of “Haemophilia”
1994-present
2. Professor C 11 of Department of Pediatrics
2002-present
3. Director of International Hemophilia Training Center-Bangkok
2002-present
4. Editorial Board of “Siriraj Medical Journal”
2013-present2
5. Editorial Board of “Srinakarin Medical Journal” 2016-present
6. Director of the Board, World Federation of Hemophilia
2019-present
Specialty
1. Pediatric hematology
2. Molecular genetics of hemophilia A & B
3. Carrier detection and prenatal diagnosis of hemophilia and other congenital
bleeding disorder
4. National registry of hemophilia and other congenital bleeding disorders
5. Genetic markers for predicting the severity of Dengue Hemorrhagic Fever
6. The use of recombinant factor VIIa in controlling massive bleeding
7. Thalassemia & hemoglobinopathies
Award
The best abstract award of young investigator from the XVI International Society of
Thrombosis and Hemostasis, Florence, Italy, 6-12 June 1997. “Vitamin K deficiency
bleeding in Thailand: A 32-year history” by Chuansumrit A, Isarangkura P, Hathirat P,
Vitamin K study group.
First Prize winner of ZLB Berhing Grant 2004 for improving the quality of life for
hemophilia patients, under the philosophy “Simple Things, Great Results” “Accurate
bedside diagnostic kit for determining hemophilia A and B” by Chuansumrit A,
Pongtanakul B, Kadegasem P, Sasanakul W, Chotsuppakarn S.
Top of third, poster presentation by the score on July 15, 2009 of the XXII
International Society of Thrombosis and Hemostasis, Boston, USA “The prominent
mutation of inversion intron 22 among sporadic hemophilia: is it worth for antenatal
screen” by Sasanakul W, Chuansumrit A.
Thailand Research Fund-Senior Research Scholar 2006-2014.
Membership
 The World Federation of Hemophilia
 The American Society of Hematology
 The International Society of Thrombosis and Hemostasis
 The Asian Society for Pediatric Research3
Publication
Original article: 319 papers (first author 128, co-author 191)
Text book chapters: 193 papers (first author 161, co-author 36)
WHO Documents: 3 papers
Publication 5 years (2015-2020)
First author
1. Chuansumrit A, Wongwerawattanakoon P. High factor VIII and von Willebrand
factor levels are not risk factors of cryptogenic arterial ischemic stroke in Thai children.
J Child Neurol 2015;30(8):1057-9.
2. Chuansumrit A, Laothamathat J, Sirachainan N, Sungkarat W, Wongwerawattana
koon P, Kumkrua P. Correlation between liver iron concentration determined by
magnetic resonance imaging and serum ferritin in adolescents with thalassaemia
disease. Paediatr Int Child Health 2016;36(3):203-8.
3. Chuansumrit A, Songdej D, Sirachainan N, Wongwerawattanakoon P, Kadegasem P,
Sasanakul W. Safety profile of a liquid formulation of deferiprone in young children
with transfusion-induced iron overload: a 1-year experience. Paediatr Int Child Health
2016;36(3):209-13.
4. Chuansumrit A, Natesirinikul R, Pongtanakul B, Tangnararatchakit K, Sirachainan N,
Tantiworavit A, Charoenkwan P, Yoksan S. Dengue infection in pediatric patients with
thalassemia: aggravation of anemia. J Hematol Transf Med 2015;25:209-19.
5. Chuansumrit A, Sasanakul W, Promsonthi P, Sirachainan N, Panburana P,
Kadegasem P, Wongwerattanakoon P. Prenatal diagnosis for haemophilia: the Thai
experience. Haemophilia 2016;22(6):880-5.
6. Chuansumrit A, Pengpis P, Mahachoklertwattana P, Sirachainan N, Poomthavorn P,
Sungkarat W, Kadegasem P, Klairit P, Wongwerawattanakoon P. Effect of iron
chelation therapy on glucose metabolism in non-transfusion-dependent thalassemia.
Acta Haematol 2017;137:20-6.
7. Chuansumrit A, Sosothikul D, Natesirinilkul R, Lektrakul Y, Charoonruangrit U;
Factor VIII Study Group. Efficacy and safety of low-dose prophylaxis of highly
purified plasma-derived factor VIII concentrate produced by the National Blood Centre,
Thai Red Cross Society. Haemophilia. 2018;24(5):e387-e390.
8. Chuansumrit A, Apiwattanakul N, Sirachainan N, Paisooksantivatana K,
Athipongarporn A, Tangbubpha N, Kadegasem P, Tangnararatchakit K, Yoksan S. The 4
use of immature platelet reaction to predict time to platelet recovery in patients with
dengue infect. Paediatr Int Child Health 2019 Dec 6:1-5. doi:
10.1080/20469047.2019.1697574
9. Chuansumrit A, Sirachainan N, Kitpoka P, Kadegasem P, Songdej D, Sasanakul W,
Wongwerawattanakoon P. The effect of blood transfusion on growth of patients with
Hb E/-thalassemia. Hemoglobin 2019;43(4-5):264-72.
Co-author
1. Simon-Loriere E, Lin RJ, Kalayanarooj SM, Chuansumrit A, Casademont I, Lin
SY, Yu HP, Lert-Itthiporn W, Chaiyaratana W, Tangthawornchaikul N,
Tangnararatchakit K, Vasanawathana S, Chang BL, Suriyaphol P, Yoksan S,
Malasit P, Despres P, Paul R, Lin YL, Sakuntabhai A. High anti-dengue virus
activity of the OAS gene family is associated with increased severity of dengue. J
Infect Dis 2015;212(12):2011-20.
2. Sirachainan N, Wijarn P, Chuansumrit A, Kadegasem P, Wongwerawattanakoon
P, Soisamrong A. Aspirin resistance in children and young adults with
splenectomized thalassemia diseases. Thromb Res 2015;135(5):916-22.
3. Chunhakan S, Butthep P, Yoksan S, Tangnararatchakit K, Chuansumrit A.
Vascular leakage in dengue hemorrhagic fever is associated with dengue infected
monocytes, monocyte activation/exhaustion, and cytokines production. Int J Vasc
Med 2015;2015:917143. doi: 10.1155/2015/917143.
4. Songdej D, Sirachainan N, Wongwerawattanakoon P, Sasanakul W, Kadegasem P,
Sungkarat W, Chuansumrit A. Combined chelation therapy with daily oral
deferiprone and twice-weekly subcutaneous infusion of desferrioxamine in children
with β- thalassemia: 3-year experience. Acta Haematol 2015;133(2):226-36.
5. Sirachainan N, Boonyatarp M, Kadegasem P, Sasanakul W, Visudtibhan A,
Natesirinilkul R, Surapolchai P, Sirachainan N, So CC, Hongeng S, Pakakasama S,
Anurathapan U, Chuansumrit A. Curative stem cell transplantation for severe Hb h
disease manifesting from early infancy: phenotypic and genotypic analyses.
Hemoglobin 2016;40(1):70-3.
6. Sirachainan N, Chuansumrit A, Kadegasem P, Sasanakul W,
Wongwerawattanakoon P, Mahaklan L. Normal hemostatic parameters in children
and young adults with α-thalassemia diseases. Thromb Res 2016;146:35-42.5
7. Manuyakorn W, Mairiang D, Sirachainan N, Kadegasem P, Kamchaisatian W,
Benjaponpitak S, Chuansumrit A. Blood coagulation and asthma exacerbation in
children. Int Arch Allergy Immunol 2016;170(2):75-83.
8. Riddell A, Chuansumrit A, El-Ekiaby M, Nair SC. Diagnostic laboratory for
bleeding disorders ensures efficient management of haemorrhagic disorders.
Haemophilia 2016;22(Suppl 5):90-5.
9. Anurathapan U, Hongeng S, Pakakasama S, Sirachainan N, Songdej D,
Chuansumrit A, Charoenkwan P, Jetsrisuparb A, Sanpakit K, Rujkijyanont P,
Meekaewkunchorn A, Lektrakul Y, Iamsirirak P, Surapolchai P, Satayasai W,
Sirireung S, Sruamsiri R, Wahidiyat PA, Ungkanont A, Issaragrisil S, Andersson
BS. Hematopoietic stem cell transplantation for homozygous β-thalassemia and β-
thalassemia/hemoglobin E patients from haploidentical donors. Bone Marrow
Transplant 2016;51(6):813-8.
10. Lertthammakiat S, Anantasit N, Anurathapan U, Sirachainan N, Kadegasem P,
Chuansumrit A. Low plasma FVII:C and activated FVII as predictive markers for
overt disseminated intravascular coagulation. Thromb Haemost 2017;117:1471-7.
11. Surapolchai P, Chuansumrit A, Sirachainan N, Kadegasem P, Leung KC, So CC.
A molecular study on the role of alpha-hemoglobin-stabilizing protein in
hemoglobin H. Disease.Ann Hematol 2017;96(6):1005-14.
12. Sirachainan N, Chuansumrit A, Sasanakul W, Yudhasompop N, Mahaklan L,
Vaewpanich J, Charoenkwan P, Kanjanapongkul S, Visudtibhan A,
Wongwerawattanakoon P. R147W in PROC gene Is a risk factor of
thromboembolism in Thai children. Clin Appl Thromb Hemost 2018;24(2):263-7.
13. Rerkswattavorn C, Sirachainan N, Songdej D, Kadegasem P, Chuansumrit A.
Preventable severe thalassemia among children. Hemoglobin 2018;42(3):148-53.
14. Wankanit S, Chuansumrit A, Poomthavorn P, Khlairit P, Pongratanakul S,
Mahachoklertwattana P. Acute effects of blood transfusion on insulin sensitivity
and beta-cell function in children with beta-thalassemia / HbE Disease. J Clin Res
Pediatr Endocrinol 2018;10(1):1-7. doi: 10.4274/jcrpe.4774
15. Leelalertlauw C, Mahachoklertwattana P, Hongeng S, Poomthavorn P. Megestrol
acetate-caused adrenal insufficiency and delayed puberty in a male adolescent with
spinal tumour. J Paediatr Child Health 2018;54(2):194-6.6
16. Pongjantarasatian S, Kadegasem P, Sasanakul W, Sa-Ngiamsuntorn K,
Borwornpinyo S, Sirachainan N, Chuansumrit A, Tanratana P, Hongeng S.
Coagulant activity of recombinant human factor VII produced by lentiviral human
F7 gene transfer in immortalized hepatocyte-like cell line. PLoS One
2019;14(8):e0220825. doi: 10.1371/journal.pone.0220825.
17. Sirivadhanakul P, Chuansumrit A, Songdej D, Kadegasem P,
Wongwerawattanakoon P, Sirachainan N. Increased endothelial activation in α-
thalassemia disease. Ann Hematol 2019;98(7):1593-602.
18. Kadegasem P, Songdej D, Lertthammakiat S, Chuansumrit A, Paisooksantivatana
K, Mahaklan L, Wongwerawattanakoon P, Tangbubpha N, Sirachainan N.
Reticulocyte hemoglobin equivalent in a thalassemia-prevalent area. Pediatr Int
2019;61(3):240-5.
19. Tangnararatchakit K, Chuansumrit A, Watcharakuldilok P, Apiwattanakul N,
Lertbunrian R, Keatkla J, Yoksan S. Daily Dengue Severity Score to Assess Severe
Manifestations. Pediatr Infect Dis J 2020;39(3):184-7.
20. Anurathapan U, Hongeng S, Pakakasama S, Songdej D, Sirachainan N, Pongphitcha
P, Chuansumrit A, Charoenkwan P, Jetsrisuparb A, Sanpakit K, Rujkijyanont P,
Meekaewkunchorn A, Lektrakul Y, Iamsirirak P, Surapolchai P, Sirireung S,
Sruamsiri R, Wahidiyat PA, Andersson BS. Hematopoietic stem cell transplantation
for severe thalassemia patients from haploidentical donors using a novel
conditioning regimen. Biol Blood Marrow Transplant 2020 Jan 11. pii: S1083-
8791(20)30012-4. doi: 10.1016/j.bbmt.2020.01.002.



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