Prof. Chan graduated from Dentistry (DMD, Cum Laude & Valedictorian 1981) and Medicine (MD, 1985) respectively from University of the East, Philippines and is currently both a registered dentist and medical doctor in Hong Kong. He joined the Department of Pediatrics of the University of Hong Kong in 1989. Then he pursued further training at the St. Jude Children’s Research Hospital, USA as a fellow from 1993 to 1996. He then obtained Dip of Palliative Medicine (1997) from University of Wales and MSc from University of Birmingham (1999). He joined the Faculty of Medicine, University of Hong Kong as Clinical Associate Professor in 1999, and was appointed as the Assistant Dean (External Affair) of the LKS Faculty of Medicine from 2004 to 2013. He was promoted to Clinical Professor in 2009. From Mar 2012 to Feb 2021, he was the Head of the Department of Paediatrics & Adolescent Medicine, HKU. He was awarded Tsao Yen-Chow Endowed Professorship of Pediatrics & Adolescent Medicine in 2013. He is currently the Director of the Molecular Laboratory for Traditional Chinese Medicine, HKU and also the Chief of Service of Departments of Pediatrics, The Hong Kong Children’s Hospital, HKU-Shenzhen Hospital & Gleneagle Hospital. He supervised >50 MSc & PhD students and published >350 full articles, 10 book chapters and 1 book. He serves as editor for 12 journals and is the immediate past Chief Editor of Hong Kong Journal of Paediatrics. He received multiple prestigious research grants with a total amount over US$ >6millions. He owned 6 patents including 4 on collagen microsphere device for the delivery of human mesenchymal stem cells and 2 on iPS cells. He has multiple International Awards (ANR, SIOP, ASPR, Endeavor Executive Award-Australian Government, Outstanding Pediatrician of APPA) for his clinical and laboratory research works on childhood neurogenic tumors and stem cells biology. His research interest includes the immunological aspects of stem cells, cancers and thalassemia. He is the Immediate Past Chairman of St Jude-VIVA-Asia Pediatric BMT Consortium, Regional Chairman (Asia, Australia & Africa) of Advance in Neuroblastoma Research, Secretary of the Asian Pediatric Hematology Oncology Group, and is the Past President of Hong Kong Pediatric Society.