Education:
1995 Bachelor’s degree, Seoul National University, College of Medicine, Seoul, Korea
2001 Master’s degree, Seoul National University, College of Medicine, Seoul, Korea
2009 Ph.D., Seoul National University, College of Medicine, Seoul, Korea
Professional Appointments:
1996.3-2000.2 Residency, Department of Pediatrics,
Seoul National University Children’s Hospital
2000.3-2001.2 Fellowship, Department of Pediatrics
Seoul National University Children’s Hospital
2001.3-2003.2 Fellowship, Department of Pediatrics, Samsung Medical Center
2003.3-2017.3 Clinical Instructor/ Assistant Professor/Associate Professor
Department of Pediatrics, Samsung Medical Center
2009.7-2011.2 Research Scholar, Department of Pediatrics
Indiana University School of Medicine, Indianapolis, IN, USA
2017.4~ Professor, Department of Pediatrics, Samsung Medical Center
Sungkyunkwan University School of Medicine, Seoul, Korea
Licensure and Certification:
1995 Medical Doctor (# 55935)
2000 Pediatric board (# 3658)
2008 Pediatric hematology and oncology special board (# 2008-056)
Major Research Interests:
Pediatric leukemias, aplastic anemia, myelodysplastic syndrome, hematopoietic stem cell transplantation, mesenchymal stem cells, new drug development
SCI/SCIE Publications (1st or corresponding author, recent 5 years)
1. Park KM, Yoo KH, Kim SK, Lee JW, Chung NG, Ju HY, Koo HH, Lyu CJ, Han SM, Han JW, Choi JY, Hong KT, Kang HJ, Shin HY, Im HJ, Koh KN, Kim H, Kook H, Baek HJ, Kim BR, Yang EJ, Lim JY, Park ES, Choi EJ, Park SK, Lee JM, Shim YJ, Kim JY, Park JK, Kong SK, Choi YB, Cho B, Lim YT. Clinical Characteristics and Treatment Outcomes of Childhood Acute Promyelocytic Leukemia in Korea: a Nationwide Multicenter Retrospective Study by Korean Pediatric Oncology Study Group. Cancer Res Treat 2021 Apr 20 [Epub ahead of print].
2. Cho HW, Ju HY, Hyun JK, Lee JW, Sung KW, Koo HH, Lim DH, Yoo KH. Conditioning with 10 Gy Total Body Irradiation, Cyclophosphamide, and Fludarabine without ATG Is Associated with Improved Outcome of Cord Blood Transplantation in Children with Acute Leukemia. J Korean Med Sci 2021;36(19):e128.
3. Kim DH, Kim DH, Bruce E Heck, Michael Shaffer, Hur J, Yoo KH. A Natural Supplement Formula Reduces Anti-Oxidative Stress and Enhances Osteo-Chondrogenic Differentiation Potential in Mesenchymal Stem Cells. J Clin Biochem Nutr 2020;66(3):206-212.
4. Lee MW, Ryu S, Kim DS, Lee JW, Sung KW, Koo HH, Yoo KH. Mesenchymal stem cells in suppression or progression of hematologic malignany: current status and challenges. Leukemia 2019;33(3):597-611.
5. Yoon JH, Yoo KH, Sung KW, Jung CW, Kim SJ, Hahn SM, Kang HJ, Lee JH, Im HJ, Ahn JS, Kook H, Cho B, Lee JW. Validation of treatment outcomes according to revised severity criteria from European Society for Blood and Marrow Transplantation (EBMT) for sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD). Bone Marrow Transplant 2019 Aug;54(8):1361-1368.
6. Lee MW, Kim DS, Kim HR, Park HJ, Lee JW, Sung KW, Koo HH. Yoo KH. Inhibition of N-myc expression sensitizes human neuroblastoma IMR-32 cells expressing caspase-8 to TRAIL. Cell Prolif 2019;52(3):e12577
7. Choi YB, Lee JW, Sung KW, Koo HH, Kim HJ, Yoo KH. Impact of day 14 peripheral blood chimerism after allogeneic hematopoietic stem cell bone transplantation on the treatment of non-malignant disease. J Korean Med Sci 2019;34(6):e46.
8. Park EG, Yi ES, Choi YB, Sung KW, Koo HH, Yoo KH. Unrelated donor hematopoietic stem cell transplantation for pediatric de novo acute myeloid leukemia with intermediate- or high-risk cytogenetics. Pediatr Transplant 2019;23(4):e13397.
9. Yi ES, Choi YB, Lee NH, Lee JW, Sung KW, Koo HH, Kang ES, Kim YJ, Yoo KH. Allogeneic Hematopoietic Cell Transplantation in Patients with Primary Immunodeficiencies in Korea: Eleven-Year Experience in a Single Center. J Clin Immunol. 2018;38:757-766.
10. Lee MW, Park YJ, Kim DS, Park HJ, Jung HL, Lee JW, Sung KW, Koo HH, Yoo KH. Human Adipose Tissue Stem Cells Promote the Growth of Acute Lymphoblastic Leukemia Cells in NOD/SCID Mice. Stem Cell Rev. 2018 Jun;14(3):451-460.
11. Ryu S, Kim DS, Lee MW, Lee JW, Sung KW, Koo HH, Yoo KH. Anti-leukemic effects of PPARγ ligands. Cancer Lett. 2018 Apr 1;418:10-19.
12. Kim DS, Lee WH, Lee MW, Park HJ, Jang IK, Lee JW, Sung KW, Koo HH, Yoo KH. Involvement of TLR3-Dependent PGES Expression in Immunosuppression by Human Bone Marrow Mesenchymal Stem Cells. Stem Cell Rev. 2018 Apr;14(2):286-293.
13. Kim DS, Jang IK, Lee MW, Ko YJ, Lee DH, Lee JW, Sung KW, Koo HH, Yoo KH. Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ. EBioMedicine. 2018 Feb;28:261-273.
14. Choi YB, Yi ES, Lee JW, Sung KW, Koo HH, Yoo KH. Immunosuppressive therapy versus alternative donor hematopoietic stem cell transplantation for children with severe aplastic anemia who lack an HLA-matched familial donor. Bone Marrow Transplant. 2017 Jan;52(1):47-52.
15. Lee NH, Choi YB, Yi ES, Lee SH, Kim HJ, Lee JW, Sung KW, Koo HH, Yoo KH. Monosomal karyotype is not a predictor of dismal outcome in childhood de novo acute myeloid leukemia. Leuk Res. 2016 Nov;50:57-62.
16. Kim DS, Park YJ, Lee MW, Park HJ, Jung HL, Sung KW, Koo HH, Yoo KH. Effect of Everolimus (RAD001) on Acute Graft-Versus-Host Disease in Mice. J Pediatr Hematol Oncol. 2016 Nov;38(8):663-664.
17. Kim DS, Ko YJ, Lee MW, Park HJ, Park YJ, Kim DI, Sung KW, Koo HH, Yoo KH. Effect of low oxygen tension on the biological characteristics of human bone marrow mesenchymal stem cells. Cell Stress Chaperones. 2016 Nov;21(6):1089-1099. Epub 2016 Aug 26.
18. Kim DS, Lee MW, Ko YJ, Park HJ, Park YJ, Kim DI, Jung HL, Sung KW, Koo HH, Yoo KH. Application of human mesenchymal stem cells cultured in different oxygen concentrations for treatment of graft-versus-host disease in mice. Biomed Res. 2016;37(5):311-317.
19. Koh KN, Yoo KH, Im HJ, Sung KW, Koo HH, Kim HS, Han JW, Yoon JH, Park HJ, Park BK, Baek HJ, Kook H, Lee JA, Lee JM, Lee KC, Kim SK, Park M, Lee YH, Lyu CJ, Seo JJ. Characteristics and Outcomes of Second Malignant Neoplasms after Childhood Cancer Treatment: Multi-Center Retrospective Survey. J Korean Med Sci. 2016;31(8):1254-61.
20. Kim DS, Lee MW, Ko YJ, Jang IK, Jeon S, Na B, Chae JJ, Sung KW, Koo HH, Yoo KH. Effect of ex vivo culture density on CXCR7 expression in human mesenchymal stem cells. Int J Clin Exp Med. 2016;9(6):10802-10810.
21. Kim DS, Lee MW, Ko YJ, Chun YH, Kim HJ, Sung KW, Koo HH, Yoo KH. Cell culture density affects the proliferation activity of human adipose tissue stem cells. Cell Biochem Funct. 2016;34:16-24.
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日期 | 时间 | 会场 | Session | 角色 | 讲题 |
---|---|---|---|---|---|
2021-12-11 | 15:20-15:40 | 血液与肿瘤专场 Hematology & Oncology |
血液与肿瘤专场 下午 Hematology & Oncology (p.m) |
讲者 Speaker | 如何提高儿童脐血移植植入的策略Strategies to improve graft performance in pediatric cord blood transplantation |
2021-12-11 | 15:40-15:55 | 血液与肿瘤专场 Hematology & Oncology |
血液与肿瘤专场 下午 Hematology & Oncology (p.m) |
讨论 Discussant | 讨论Discussion |