Wiparat Manuyakorn
Ramathibodi Hospital, Mahidol University, Bangkok, Thailand |
免疫学
Educational Background
May 1992-April 1998
Medical Degree
First class honors
Faculty of Medicine, Chulalongkorn University
Bangkok Thailand
Post graduate training
October 2009-
December 2011
Doctor of Philosophy
Division of Infection, Inflammation and Immunity,
Faculty of Medicine, University of Southampton
June 2004- May 2006 Pediatric Allergy and
Immunology Clinical
Fellow
Department of Pediatrics,
Faculty of Medicine, Ramathibodi Hospital,
Mahidol University, Bangkok, Thailand
June 2001- May 2004 Residency in Pediatrics
Department of Pediatrics,
Faculty of Medicine, Chulalongkorn University Bangkok
Thailand
June 2001- May 2003 Master of Science in
Pediatrics
Department of Pediatrics,
Faculty of Medicine, Chulalongkorn University Bangkok
Thailand
Licensure & Exam
Board Certfied
2007
Diplomate of Thai Board of Pediatric Allergy and Immunology, Medical Council of Thailand
2006
Certificate in Pediatric Allergy and Immunology, Ramathibodi Hospital, Mahidol University
2004
Diplomate of Thai Board of Pediatrics, Medical Council of Thailand
2002
Certificate in Basic Science of Pediatrics
1998
Doctor of Medicine
Medical License2004-present
Thai Pediatric License
1998-present
Thai Medical License: License number 23229
Awards and honors
June, 2010 Received learning curve grant from Nutricia Ltd for abstract presentation and
attendance the 29th congress of the European Academy of Allergy and Clinical
Immunology, London UK
June, 2010 Won poster abstract prize at the 29th congress of the European Academy of
Allergy and Clinical Immunology, London UK
Sep, 2009
Received Travel Grant Awarded from European Academy of Allergy and Clinical
Immunology for abstract presentation and attendance in Hymemoptera Venom
Allergy School Ancona, Italy
Dec, 2007
Received Travel Grant Awarded from Allergy and Immunology Society of Thailand for
abstract presentation and attendance in 2007 World Allergy Congress Bangkok,
Thailand
Feb, 2006
Received the International Fellows-in-Training Travel Scholarships from The
American Academy of Allergy Asthma&Immunology for abstract presentation and
attendance in 2006 AAAAI Annual Meeting Miami Beach, Florida
Feb, 2004
Best research award from Department of Pediatrics,
Faculty of Medicine, Chulalongkorn University Bangkok Thailand
Work Experience
Dec 2019-present Head of Pediatric Allergy and Immunology Division
Apr 2017-present
Jan 2017-present
Responsibility
Sep 2013-Dec 2016
Responsibility
Aug 2007-Sep 2013
Responsibility
The Vice Department of Pediatrics in Research and International Relation.
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital,
Mahidol University, Bangkok, Thailand
-Associate professor
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital,
Mahidol University, Bangkok, Thailand
-Assistant professor
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital,
Mahidol University, Bangkok, Thailand
- Lecturer
July 2006-July 2007
Responsibility
Department of Pediatrics, Royal irrigation Hospital, Nonthaburi, Thailand
- Pediatric Allergist
Sep 1999-May 2001
Responsibility
Department of Pediatrics, Faculty of Medicine, Srinakarinthviroj University
Bangkok Thailand
- Lecturer
April 1999-Sep 1999
Responsibility
Department of Pediatrics, Saraburi Hospital,Saraburi province, Thailand
- General physician
April 1998 – May 1999
Responsibility
Saraburi Hospital,Saraburi province, Thailand
- Intern
Professional Organization
1998 – present
Member of Medical Council of Thailand
2004 – present
Member of the Pediatric Society of Thailand
2004 – present
Member of the Thai Royal College of Pediatrics
2005 – present
Member of the Allergy and Immunology Society of Thailand 2005 – present Member of the American Academy of Allergy Asthma&Immunology
2005 – present Member of the European Academy of Allergology and Clinical
Immunolgy organization
2006 – present Member of World Allergy Organization
Bibliography:
1.Deerojanawong J, Manuyakorn W, et al. Randomized Controlled Trial of Salbutamol
Aerosol Therapy Via Metered Dose Inhaler-Spacer vs. Jet Nebulizer in Young Children
With Wheezing. Pediatr Pulmonol 2005;39(5):466-72
2.Manuyakorn W, Kamchaisatian W, Atamasirikul K, Sasisakulporn C, Direkwattanachai C,
Benjaponpitak S. Serum TGFβ1 in atopic asthma. Asian Pac J Allergy Immunol. 2008
Dec;26(4):185-9.
3.Manuyakorn W, Direkwattanachai C, Benjaponpitak S, Kamchaisatian W, Sasisakulporn C
,Teaesomboonkit W. Sensitivity of Turbutester® and Accuhaler® Tester in Asthmatic
children and adolescents Pediatr Int.2010 Feb;52(1):118-25
4.Kerddonfak S, Manuyakorn W, Kamchaisatian W, Sasisakulporn C, Teawsomboonkit W,
Benjaponpitak S. The stability and sterility of epinephrine prefilled syringe. Asian Pac J
Allergy Immunol. 2010 Mar;28(1):53-7.
5.Charoenying Y, Kamchaisatian W, Atamasirikul K, Direkwattanachai C, Manuyakorn W,
Benjaponpitak S. Cytokine responses during exacerbation compared with stable phase in
asthmatic children. Asian Pac J Allergy Immunol. 2010 Mar;28(1):35-40.
6.Yang Y, Wicks J, Haitchi HM, Powell RM, Manuyakorn W, Howarth PH, Holgate ST, Davies DE.
Regulation of a Disintegrin and Metalloprotease-33 Expression by Transforming Growth
Factor-β. Am J Respir Cell Mol Biol. 2012 May;46(5):633-40.
*7.Manuyakorn W, Howarth PH, Holgate ST. Airway remodelling in asthma and novel
therapy. Asian Pac J Allergy Immunol. 2013 Mar;31(1):3-10.
8.Manuyakorn W, Siripool K, Kamchaisatian W, Pakakasama S, Visudtibhan A, Vilaiyuk S, Rujirawat
T, Benjaponpitak S. Phenobarbital-induced severe cutaneous adverse drug reactions are
associated with CYP2C19*2 in Thai children. Pediatr Allergy Immunol 2013;24:299-303
9. Manuyakorn W.Airway remodelling in asthma: role for mechanical forces. Asia Pac
Allergy. 2014 Jan;4(1):19-24.
10. Sookrung N, Wong-Din-Dam S, Tungtrongchitr A, Reamtong O, Indrawattana N, Sakolvaree Y,
Visitsunthorn N, Manuyakorn W, Chaicumpa W. Proteome and Allergenome of Asian Wasp,
Vespa affinis, Venom and IgE Reactivity of the Venom Components. J Proteome Res. 2014 Mar
7;13(3):1336-44.
11. Andriotisa OG, Manuyakorn W, Zekonyted J, Katsamenisa OL, Fabria S, Howarth PH, Davies DE,
Thurner PJ. Nanomechanical assessment of Human and murine collagen fibrils via atomic
force microscopy cantilever-based nanoindentation. Journal of the Mechanical Behavior ofBiomedical Materials, 2014 Nov;39:9-26.
*12. Manuyakorn W, Benjaponpitak S, Siripool K, Prempunpong C, Singvijarn P, Kamchaisatian W,
Supapannachart S.Cow milk protein allergy presenting as feeding intolerance and
eosinophilia: case reports of three preterm neonates.Paediatr Int Child Health. 2015
Nov;35(4):337-41.
13. Manuyakorn W, Sinitkul R, Treepongkaruna S, Kamchaisatian W, Vilaiyuk S, Srisala S,
Benjaponpitak S. In vitro cytokine changes after pediatric liver transplantation. Asian Pac J
Allergy Immunol. 2015 Mar;33(1):52-8.
*14. Manuyakorn W, Padungpak S, Luecha O, Kamchaisatian W, Sasisakulporn C, Vilaiyuk S,
Monyakul V, Benjaponpitak S. Assessing the efficacy of a novel temperature and humidity
control machine to minimize house dust mite allergen exposure and clinical symptoms in
allergic rhinitis children sensitized to dust mites: a pilot study .Asian Pac J Allergy Immunol.
2015 Jun;33(2):129-35.
*15. Suvichapanich S, Jittikoon J, Wichukchinda N, Kamchaisatian W, Visudtibhan A, Benjapopitak S,
Nakornchai S, Manuyakorn W, Mahasirimongkol S. Association analysis of CYP2C9*3 and
phenytoin-induced severe cutaneous adverse reactions (SCARs) in Thai epilepsy children.
J Hum Genet. 2015 2015 Aug;60(8):413-7.
16. Vilaiyuk S, Soponkanaporn S, Jaovisidha S, Benjaponpitak S, Manuyakorn W.
A retrospective study on 158 Thai patients with juvenile idiopathic arthritis followed in a
single center over a 15-year period.
Int J Rheum Dis. 2015 Jul 14. doi: 10.1111/1756-185X.12637. [Epub ahead of print]
17. Anantasit N, Manuyakorn W, Anantasit N, Choong K, Preuthipan A.Spontaneous
Pneumomediastinum in Non-Asthmatic Children with Exercise-Induced
Bronchoconstriction. Am J Case Rep. 2015 Sep 22;16:648-51.
*18. Manuyakorn W, Benjaponpitak S, Kamchaisatian W, Vilaiyuk S, Sasisakulporn C, Jotikasthira
W.
Pediatric anaphylaxis: triggers, clinical features, and treatment in a tertiary-care
hospital. Asian Pac J Allergy Immunol. 2015 Dec;33(4):281-8.
19. Puranitee P, Kamchaisatian W, Manuyakorn W, Vilaiyuk S, Laecha O, Pattanaprateep O,
Benjaponpitak S. Direct medical cost of Thai pediatric asthma management: a pilot study.
Asian Pac J Allergy Immunol. 2015 Dec;33(4):296-300.
20. Manuyakorn W, Smart DE, Noto A, Bucchieri F, Haitchi HM, Holgate ST, Howarth PH, Davies
DE. Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing
Profibrotic and Inflammatory Responses. PLoS One. 2016 Apr 21;11(4):e0153926. doi:
10.1371/journal.pone.0153926. eCollection 2016.
21. Manuyakorn W, Mairiang D, Sirachainan N, Kadegasem P, Kamchaisatian W, Benjaponpitak S,
Chuansumrit A. Blood Coagulation and Asthma Exacerbation in Children. Int Arch Allergy
Immunol. 2016 Jul 26;170(2):75-83.
*22. Manuyakorn W, Singvijarn P, Benjaponpitak S, Kamchaisatian W, Rerkpattanapipat T,
Sasisakulporn C, Jotikasthira W.Skin testing with β-lactam Antibiotics for Diagnosis of β-
lactam Hypersensitivity in Children. Asian Pac J Allergy Immunol. 2016 Aug 16. doi:
10.12932/AP0750.*23. Manuyakorn W, Mahasirimongkol S, Kamchaisatian W, Wattanapokayakit S, Inunchot W,
Somboonyosdech C, Likkasittipan P, Visudtibhan A, Wichukchinda N, Benjaponpitak S. Association
of HLA Genotypes with Phenobarbital Hypersensitivity in Children. Epilepsia. 2016
Oct;57(10):1610-1616.
*24. Manuyakorn W, Benjaponpitak S, Kamchaisatian W, Sasisakulporn C, Jotikasthira W.
Safety and efficacy of ant rush immunotherapy in children.Asian Pac J Allergy Immunol. 2016
Dec 12. doi: 10.12932/AP0831.
25. Puranitee P, Siwarom S, Plitponkarnpim A, Manuyakorn W, Sinitkul R, Arj-Ong Vallipakorn S.
Association of indoor air quality and preschool children's respiratory symptoms.
Asian Pac J Allergy Immunol. 2016 Dec 12. doi: 10.12932/AP0838.
*26. Matangkasombut P, Padungpak S, Thaloengsok S, Kamchaisatian W, Sasisakulporn C,
Jotikasthira W, Benjaponpitak S, Manuyakorn W. Detection of β-lactoglobulin in human
breast-milk 7 days after cow milk ingestion. Paediatr Int Child Health. 2017 Aug;37(3):199-
203.
*27. Kreetapirom P, Hongeng S, Manuyakorn W, Anurathapan U, Pakakasama S, Sirachainan N,
Andersson BS.Successful HLA haploidentical HSCT with post-transplant cyclophosphamide
in Wiskott-Aldrich syndrome. Bone Marrow Transplant. 2017 Jun;52(6):913-914.
28. Maverakis E, Wang EA, Shinkai K, Mahasirimongkol S, Margolis DJ, Avigan M, Chung WH,
Goldman J, La Grenade L, Pirmohamed M, Shear NH, Tassaeeyakul W, Hoetzenecker W,
Klaewsongkram J, Rerkpattanapipat T, Manuyakorn W, Yasuda SU, Sharon VR, Sukhov A,
Micheletti R, Struewing J, French LE, Cheng MY.Stevens-Johnson Syndrome and Toxic
Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a
National Institutes of Health Working Group. JAMA Dermatol. 2017 Jun 1;153(6):587-592.
*29. Manuyakorn W, Itsaradisaikul S, Benjaponpitak S, Kamchaisatian W, Sasisakulporn C,
Jotikasthira W, Matangkasombut P.Mosquito Allergy in Children: Clinical features and
limitation of commercially-available diagnostic tests. Asian Pac J Allergy Immunol. 2017
Dec;35(4):186-190.
*30. Manuyakorn W, Bamrungchaowkasem B, Ruangwattanapaisarn N, Kamchaisatian W,
Benjaponpitak S. Optimal needle length for epinephrine prefilled syringe in children. Ann
Allergy Asthma Immunol. 2017 Jun;118(6):740-741.e1.
*31. Manuyakorn W, Klangkalya N, Kamchaisatian W, Benjaponpita S, Sasisakulporn C, Jotikasthira
W. Efficacy of Nasal Cellulose Powder in the Symptomatic Treatment of Allergic Rhinitis:
A Randomized, Double-Blind, Placebo-Controlled Trial. Allergy Asthma Immunol Res. 2017
Sep;9(5):446-452.
32. Potiwat R, Tanyaratsrisakul S, Maneewatchararangsri S, Manuyakorn W, Rerkpattanapipat T,
Samung Y, Sirivichayakul C, Chaicumpa W, Sitcharungsi R.Solenopsis geminata (tropical fire
ant) anaphylaxis among Thai patients: its allergens and specific IgE-reactivity.Asian Pac J
Allergy Immunol. 2018 Jun;36(2):113-119.
33. Lakupoch K, Manuyakorn W, Preutthipan A, Kamalaporn H.The effectiveness of newly developed written asthma action plan in improvement of
asthma outcome in children. Asian Pac J Allergy Immunol. 2018 Jun;36(2):88-92.
*34. Manuyakorn W, Bamrungchaowkasem B, Ruangwattanapaisarn N, Kamchaisatian W,
Benjaponpitak S. Needle length for epinephrine prefilled syringes in children and
adolescents: Is it one inch? Asian Pac J Allergy Immunol. 2018 Jun;36(2):113-119.
35. Sinitkul R, Manuyakorn W, Kamchaisatian W, Vilaiyuk S, Benjaponpitak S, Lertudompholwanit
C, Treepongkaruna S. De novo food allergy in pediatric liver transplantation recipients.
Asian Pac J Allergy Immunol. 2018 Sep;36(3):166-174.
*36. Manuyakorn W, Tanpowpong P.Cow milk protein allergy and other common food
allergies and intolerances. Paediatr Int Child Health. 2019 Feb;39(1):32-40.
*37. Mukdjindapa P, Manuyakorn W, Kiewngam P, Sasisakulporn C, Pongchaikul P, Kamchaisatian
W, Benjaponpitak S. Reference value of Forced Oscillation Technique for healthy preschool
children. Asian Pac J Allergy Immunol. 2018 Dec 9. doi: 10.12932/AP-110618-0334.
*38 Singvijarn P, Manuyakorn W, Mahasirimongkol S, Wattanapokayakit S, Inunchot W,
Wichukchinda N, Suvichapanich S, Kamchaisatian W, Benjaponpitak S.
Association of HLA genotypes with Beta-lactam antibiotic hypersensitivity in children.
Asian Pac J Allergy Immunol. 2019 Apr 23. doi: 10.12932/AP-271118-0449.
*39. Janjindamai C, Manuyakorn W, Anurathapan U, Pakakasama S, Wattanasirichaigoon D,
Kamchaisatian W, Benjaponpitak S, Hongeng S.
Successful haploidentical hematopoietic stem cell transplantation with post-transplant
cyclophosphamide in a child with X-linked chronic granulomatous disease: A first report
in Asia.
Asian Pac J Allergy Immunol. 2019 Nov 3. doi: 10.12932/AP-290419-0551.
*40. Ittiwut C, Manuyakorn W, Tongkobpetch S, Benjaponpitak S, Fisher MR, Milner JD, Lyons JJ,
Suphapeetiporn K, Shotelersuk V.
Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody
Deficiency Requiring Monthly IVIG Infusions.
J Clin Immunol. 2020 Jan;40(1):227-231. doi: 10.1007/s10875-019-00693-6.
*41. Swangtrakul N, Manuyakorn W, Mahachoklertwattana P, Kiewngam P, Sasisakulporn C,
Jotikasthirapa W, Kamchaisatian W, Benjaponpitak S.
Effect of vitamin D on lung function assessed by forced oscillation technique in asthmatic
children with vitamin D deficiency: A randomized double-blind placebo-controlled trial.
Asian Pac J Allergy Immunol. 2019 Dec 14. doi: 10.12932/AP-010519-0553
42. Sirimontakan T, Manuyakorn W, Kamalaporn H, Wattanarungsun P, Chonpaisan K, Thongkum
K, Singvijarn P, Phumethum S.
Efficacy of a newly developed cartoon video on dry powder inhaler technique: a
multicenter study.
Asian Pac J Allergy Immunol. 2019 Dec 14. doi: 10.12932/AP-240719-0607.
43. Opasawatchai A, Yolwong W, Thuncharoen W, Inrueangsri N, Itsaradisaikul S, Sasisakulporn C,
Jotikasthira W, Matangkasombut O, Reamtong O, Manuyakorn W, Songnuan W, Matangkasombut
P. Novel salivary gland allergens from tropical mosquito species and IgE reactivity in
allergic patients. World Allergy Organ J. 2020 Feb 17;13(2):100099. doi:
10.1016/j.waojou.2020.100099. eCollection 2020 Feb.*44. Kreetapirom P, Kiewngam P, Jotikasthira W, Kamchaisatian W, Benjaponpitak S, Manuyakorn
W.
Forced oscillation technique as a predictor for loss of control in asthmatic children.
Asia Pac Allergy. 2020 Jan 17;10(1):e3. doi: 10.5415/apallergy.2020.10.e3.
*44. Manuyakorn W, Likkasittipan P, Wattanapokayakit S, Suvichapanich S, Inunchot W,
Wichukchinda N, Khongkhatithuml C, Thampratankul L, Kamchaisatian W, Benjaponpitak S,
Mahasirimongkol S. Association of HLA genotypes with phenytoin induced severe cutaneous
adverse drug reactions in Thai children. Epilepsy Res. 2020 May;162:106321. doi:
10.1016/j.eplepsyres.2020.106321. Epub 2020 Mar 13.
* 45 Traiyan S, Manuyakorn W, Kanchongkittiphon W, Sasisakulporn C, Jotikasthira W, Kiewngam
P, Kamchaisatian W, Benjaponpitak S. Skin Prick Test Versus Phadiatop as a Tool for
Diagnosis of Allergic Rhinitis in Children. Am J Rhinol Allergy. 2020 Jun 27:1945892420938300.
doi: 10.1177/1945892420938300.
* 46. Athipongarporn A, Ittiwut C, Manuyakorn W, Assawawiroonhakarn S, Larbcharoensub N,
Shotelersuk V. Diagnosis of Hyper IgM syndrome in a Previously Healthy Adolescent Boy
Presented with Cutaneous and Cerebral Cryptococcosis. Pediatr Infect Dis J. 2021
Jan;40(1):e18-e20.
* 47. Rattanamanee T, Lumjiaktase P, Kemawichanura N, Kiewgnam P, Jotikasthira W, Manuyakorn
W. Regulatory T cell and cytokine changes in children undergoing 3 days rush venom
immunotherapy. Asian Pac J Allergy Immunol. 2020 Oct 17. doi: 10.12932/AP-140520-0843.
48. Saengow VE, Chiangjong W, Khongkhatithum C, Changtong C, Chokchaichamnankit D,
Weeraphan C, Kaewboonruang P, Thampratankul L, Manuyakorn W, Hongeng S, Srisomsap C,
Svasti J, Chutipongtanate S, Visudtibhan A.Proteomic analysis reveals plasma haptoglobin,
interferon-γ, and interleukin-1β as potential biomarkers of pediatric refractory epilepsy.
Brain Dev. 2020 Nov 30:S0387-7604(20)30310-7. doi: 10.1016/j.braindev.2020.11.001.
49. Siripornpanich S, Chongviriyaphan N, Manuyakorn W, Matangkasombut P.
Zinc and vitamin C deficiencies associate with poor pulmonary function in children with
persistent asthma. Asian Pac J Allergy Immunol. 2020 Dec 2. doi: 10.12932/AP-100620-0878.
50. Kanchongkittiphon W, Kittinon K, Wanitchakorn A, Benjaponpitak S, Manuyakorn W.
Favorable Response to Interferon-α in Infantile-onset Idiopathic Hypereosinophilic
Syndrome Complicated by Status Epilepticus During Treatment.
J Pediatr Hematol Oncol. 2021 Jan 11. doi: 10.1097/MPH.0000000000002052.
* as coresponding author
Invited speaker for international conference
1. Evidence-based in the management of anaphylaxis at Asia Pacific Association of Pediatric
Allergy, Respirology and Immunology 2013 (APAPARI 2013) Bangkok, Thailand October 2-4 2013
2. Airway Remodelling in Asthma: Role for Physical Force at the 2013 Asia Pacific Congress of
Allergy, Asthma and Clinical Immunology (APCAACI 2013) Taipei, Taiwan November 14- 17, 20133. Preschool Wheezing: Is it Asthma? at 15th Malaysian Congress and Exhibition on Allergy and
Immunology at Bayview Hotel, Georgetown Penang, Malasia, April 4 - 6 2014
4.Severe asthma in children: definition and differences between adults and children at
14th World Allergy Congress (WAC 2015) Seoul, South Korea, October 14-17, 2015
5. Pharmacogenetic Testing for Aromatic Anticonvulsant induced Cutaneous Adverse
Drug Reaction at Joint Congress of Asia Pacific Association of Allergy, Asthma and Clinical
Immunology (APAAACI) and Asia Pacific Association of Pediatric Allergy, Respirology & Immunology
(APAPARI) 2016 17th to 20th October 2016, at Shangri-La Hotel in Kuala Lumpur (19th October
2016, 1500hrs – 1600hrs)
6. Epinephrine in anaphylaxis the current and unresolved issues at Joint Congress of Asia
Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI) and Asia Pacific Association
of Pediatric Allergy, Respirology & Immunology (APAPARI) 2018 11st to 14th October 2018, at the
Centara Grand & Bangkok Convention Centre Bangkok
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| 日期 | 时间 | 会场 | Session | 角色 | 讲题 |
|---|---|---|---|---|---|
| 2021-12-11 | 10:35-11:55 | 免疫专场 Immunology |
免疫专场-上午 Immunology (a.m.) |
主持 Moderator | |
| 2021-12-11 | 11:40-11:55 | 免疫专场 Immunology |
免疫专场-上午 Immunology (a.m.) |
讨论 Discussant | 讨论Discussion |
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