Debbie Gipson
University of Michigan
9/1980 – 5/1984
B.S. Chemistry. University of Evansville, Evansville, IN
8/1984 – 6/1986*
M.D. Indiana University School of Medicine, Indianapolis, IN
7/1987 – 6/1989
*1986-1987, 12-month maternity leave
8/1996 – 5/1998
M.S. Epidemiology.
University of Washington School of Public Health, Seattle, WA
Postdoctoral Medical Training
7/1989 – 6/1992
Pediatrics Residency
Indiana University Medical Center, Indianapolis, IN
7/1992 – 6/1993
Chief Resident, Pediatrics
Indiana University Medical Center, Indianapolis, IN
8/1995 – 5/1998
Pediatric Nephrology Fellowship
Children’s Hospital and Medical Center, Seattle, WA
Certification and Licensure
Medical Licensure
10/2009 – present
State of Michigan #4301095473
6/1999 – 2010
State of North Carolina #9900842
8/1993 – 1999
State of Washington
7/1990 – 1998
State of Indiana
Board Certification
10/2001 – present
American Board of Pediatrics, Pediatric Nephrology #000580, active
6/1993 – 6/2007
American Board of Pediatrics #050977, inactive
Academic Appointments
2014 – present
Professor of Pediatrics with tenure
University of Michigan
9/2012 – 6/2015
Director, Honest Broker Office, University of Michigan Medical
School
12/2009 – 2014
Associate Professor of Pediatrics
University of Michigan2
6/2006 – 11/2009
Associate Professor of Medicine and Pediatrics
UNC School of Medicine
Division of Nephrology and Hypertension
9/2006 – 11/2009
Adjunct Associate Professor
UNC School of Public Health, Department of Epidemiology
5/2003 – 6/2009
Pediatric Nephrology Sub-Specialty Training Program Director
UNC School of Medicine, Department of Medicine,
Division of Nephrology and Hypertension
9/1999 – 11/2009
Training Faculty
UNC Renal Epidemiology Training Program (T32)
6/1999 – 6/2006
Assistant Professor of Medicine and Pediatrics
UNC School of Medicine,
Division of Nephrology and Hypertension
6/1999 – 6/2006
Clinical Assistant Professor
UNC School of Public Health, Department of Epidemiology
8/1993 – 7/1995
Pediatrician
Yakima Valley Farm Workers Clinic, Toppenish, WA
National Health Service Corps
Research Interests
1. Nephrotic Syndrome
2. Focal Segmental Glomerulosclerosis
3. Clinical Trials
4. Chronic Kidney Disease
5. End Stage Kidney Disease
6. Patient Reported Outcomes
Grant Reviews
2019 NIH: 2019/01 ZDK1 GRB-M (J2)
2015 Lupus Foundation
2014 UK British Council
2014 WelcomeTrust
2012 NIH: ZRG1 DKUS-G 11 B, Nephrology Research and Small Business Applications
2012 NIH: ZHD1DSRK10 Molecular Mechanisms of Adverse Metabolic Drug Effects in
Children and Adolescents (R01)
2012 NEPTUNE Pilot Grants
2012 NephCure Foundation
2012 Lupus Foundation of America
2011 Lupus Foundation of America
2007 NIH R21 PAR06-113
2005 NIH U01 Sickle Cell Disease Consortium 1U10HL083748-01
2005 Thrasher Research Fund
Research – Active
Title: Preparing a clinical outcomes assessment set for nephrotic syndrome [Prepare-NS]
Goals: The goals of this project are to develop a validated set of clinical outcome measures for 3
fluid overload in nephrotic syndrome in support of drug development.
Role: Principal Investigator (mPI) (Gipson, UM; Peipert, Northwestern)
Dates: 5/1/2021-4/30/2026
Effort 20%
Source: FDA: 1UG3FD007308-01
Title: Cure Glomerulonephropathy Consortium-2 DCC (CureGN)
Goals This Data Coordinating Center grant will support the implementation of an international
cohort of primary glomerular disease patients and healthy controls to advance multidisciplinary
collaborative research in children and adults with FSGS, MN, MCD and IgA nephropathy
compared with healthy controls.
PI: Co-PIs (Gipson, Kretzler, Robinson, Gillespie)
Dates: 9/16/13 – 5/31/24
Effort: 10%
Source NIH/NIDDK 2UM1DK100845-07
Title: Clinical Phenotyping and Biobanking Core for CKD
Goals: Provide infrastructure, data and biobanked specimens to support kidney disease.
PI: Pennathur
Role: Co-Investigator, Pediatric Lead
Dates: 02/2019-01/2021
Effort 2%
Source RPC2 Pre-competitive consortium/UM
Title: Nephrotic Syndrome Rare Disease Clinical Research Network 1,2,3 (NEPTUNE)
Goals: Nephrotic Syndrome RDCRN, a multidisciplinary research and education platform that
brings together clinical and translational scientists and two lay research and patient education
foundations, aimed at beginning to better study and educate patients with FSGS, MN, and MCD.
PI:
M. Kretzler
Role: Co-Director for pediatric cohort, Co-I
Dates: 7/2014 – 6/2024
Effort: 10%
Source: NIH/NCATS, NIDDK, NephCure 2U54DK083912-11
Title: TNF Precision Medicine Trial
Goals: Design, coordinate and conduct multisite open label clinical trial to test the biomarker
response to TNF inhibitor therapy in patients with FSGS or treatment resistant MCD.
Role: PI
Dates: 2/1/2018-12/29/2021
Source: University of MI, Drug Repurposing Grant, MICHR
Title: Accelerating Cures Institute EHR Registry and Quality Analytics
Goals: Provide administrative, clinical and data coordinating center support for the clinical trials
network, electronic health record patient registry, analytic support for consortium prioritized
research focused on patients with proteinuric kidney disease.
Role: PI
Dates: 1/1/2018 – 12/31/2022
Source: Levine Children’s Hospital Foundation
Title: Efficacy and Safety of RE-021 In Patients With FSGS
Goals: Clinical trial of novel agent for proteinuric patients with FSGS4
Role: Site PI
Dates: 05/30/14 – 12/31/19
Source: CTI Clinical Trial and Consulting Services / ReTrophin, Inc
Title: CDC CKD Surveillance Initiative
Goals: To track and report on national trends in CKD risk factors, epidemiology, and processes
of care for national use in education and policy efforts.
PI: R Saran
Role: Co-Investigator
Dates: 2014-2021
Effort: 2%
Source: CDC
Title: Cardinal/Eagle Clinical trial of Bardoxolone in patients with Alport syndrome
Goals: To test the efficacy and safety of Bardoxolone in Alport syndrome in a randomized,
double blind parallel arm clinical trial [Cardinal]/followed by an open label extension trial
[Eagle]
Role: Site PI
Dates: 2019-2023
Source: Reata Pharmaceuticals
Effort 2%
NS PRO Consortium
Goals: The goal of working collaboratively under common terms and conditions established for
the development and validation of patient outcome survey instruments to provide information
critical to the assessment of the efficacy of treatment in clinical trials and other clinical care
settings.
Role: Consortium Executive Committee Member and co-director
Dates: 3/1/2019 – 2/29/2024
Source: Various Sponsors
Research-Complete
Title: PRO and Clinician Reported Outcome development for children and adults with FSGS or
minimal change disease.
Goals: To elicit and transform concepts to instruments for use in the assessment of patient
reported- and clinician reported- outcome measures for children and adults with proteinuric
kidney disease.
Role: PI
Dates: 06/01/2018 – 12/31/2019
Sponsor: Goldfinch Bio
Title: Coordinating Center for Clinical Study Protocol A Phase 2 Multicenter, Open Label,
Randomized Study of Two Titration Regimens of Oral CXA-10 in Subjects with FSGS
Goals: To coordinate clinical trial conduct, data collection and analysis for the phase 2 study of
CXA-10 in adults and adolescents with incident FSGS
Role: Site PI
Dates: 2017-8/2020
Effort:25%
Source: Complexa5
Title: Patient Powered Research Networks (PPRN) in Nephrotic Syndrome - II
Goals: Expand the national research network of patients affected by nephrotic syndrome
PI: Cope
Role: Co-Investigator
Dates: 11/15-10/18
Effort: 5%
Source: PCORI
Title: NephCure Accelerating Cures Institute
Goals: Establish and operate a clinical trials network, outcomes development consortium, data
warehouse and coordinating center to support the testing of new therapies for patients with
proteinuric kidney disease.
Role: PI/Director
Dates: 04/01/2015 – 12/31/2017
Effort: 25%
Source: NephCure Kidney International
Title: Cohort Study of Children with Chronic Kidney Disease (C-KID-I, C-KID-II, CKiD-III)
Goals: Assess the risk factors for progression of chronic kidney disease in 540 children and
document the co-morbidities including cognition, cardiovascular and growth dysfunction.
Role Site PI 1/16-1/19. Transitioned PI to mentee Z. Modi 1/19 (Study PI: S. Furth and B.
Warady)
Dates: 1/2010 – 12/2023
Source: NIH/NIDDK U01-DK-66116
Title: O’Brien Kidney Center
Goals: Provide infrastructure, training, pilot grant, cohort, biobank and systems biology analytic
support to advance research in kidney disease.
PI: Brosius (13-16);Pennathar (16-18)
Role: Co-Investigator, Pediatric Lead
Dates: 9/15/13 – 7/31/18
Effort 7%
Source NIH/NIDDK 2P30DK081943-06
Title: A Randomized Controlled Trial of Rituximab versus Cyclosporine in the Treatment of
Idiopathic Membranous Nephropathy - MENTOR
Goals: Clinical trial of novel agent for proteinuric patients with Membranous Nephropathy
Site PI: Gipson, Patrick
Role: Co-investigator and study design consultant
Dates: 12/12 – 12/01/17
Source: Mayo Clinic
Title: Development of a Novel Proteinuria Endpoint for FSGS
Goals: FSGS is a rare kidney disease with a need for surrogate endpoints for clinical trials. This
study will use existing data sources to develop and validate a proteinuria endpoint for consideration
as potentially acceptable for drug development programs.
Role: PI
Dates: 2016-5/2017
Source: Retrophin
Effort 2.5%6
Title: Learning Health System Network (LHSnet)
Goals: This is a clinical data research network within the PCORnet national patient centered
research structure. In partnership with the LHSnet sites, patient medical record data will be
transformed to a common data model, research priorities will be identified with multiple
stakeholders, and research conducted using the networked health systems, practices and patient
powered research networks that comprise this research infrastructure.
PI: V. Roger (Mayo Clinic)
Role: Co-investigator and Clinical Trials Committee lead
Dates: 11/8/2015-12/31/2016
Effort 10%
Source: PCORI
Title: Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia
Goals: Assess the safety and efficacy of furosemide premature infants.
PI: Matthew Laughon, MD (UNC)
Role: Nephrology Subject Matter Expert, DCC
Dates: 1/1/2016 – 5/31/2019
Effort 2.5%
Source: NICHD
Title: USRDS
Goals: This program provides data analysis, produces the Annual Data Report, and supports
special analysis for the national USRDS program.
PI: Saran
Role: Co-Investigator
Dates: 2/2014 – 8/2019
Effort: 5%
Source: NIH/NIDDK HHSN2762014 00001C
Title: Phase II Randomized, Placebo-Controlled, Double-Blind, Parallel Arms with Switchover,
Pilot Study to Evaluate the Efficacy and Safety of Intravenous Abatacept in Treatment of Resistant
Nephrotic Syndrome (FSGS/MCD)
Goals: Assess the efficacy and safety of Abatacept novel therapy for treatment resistant nephrotic
syndrome.
Role: Site PI and Steering Committee member
Dates: 04/15/16 – 12/31/19
Source: BMS
Title: Patient Powered Research Networks (PPRN) in Nephrotic Syndrome - II
Goals: Expand the national research network of patients affected by nephrotic syndrome
PI: Cope
Role: Co-Investigator
Dates: 11/15-10/18
Effort: 5%
Title: Study of Losmapimod to Reduce Proteinuria in Corticosteroid or Calcineurin Inhibitor
Resistant Idiopathic Focal Segmental Glomerulosclerosis (FSGS) Patients
Goals: Proof of concept trial of novel p38 MAPK inhibitor in FSGS
Role: Site PI and study design consultant7
Dates: 6/26/14 – 06/25/16
Source: GSK
Title: Pediatric Terminology Harmonization Initiative
Goals: Develop a set of pediatric terminology fit for use in research, clinical, safety and quality
settings.
PI: S. Hirschfeld, NICHD/NIH
Role: Working group lead for Pediatric Adverse Event Terminology; Working group lead for
Pediatric Nephrology
Dates: 9/2014 – 8/2015
Effort 3%
Source: NIH/NICHD
Title: PROMIS (Patient Reported Outcomes Measurement Information System) II
Goals: To develop a national resource for evaluation of patient reported outcomes in children.
This award extends the validation of the newly developed PROMIS tool using a prospective,
longitudinal cohort design.
PI: D. Dewalt/Reeve
Effort: 10%
Role: Project PI for Nephrotic Syndrome Cohort
Dates: 10/2009 – 7/2014; NCE 7/2015
Source: NIH/NIAMS 2U01AR05218106
Title: Development of a Patient Centered Decision Tool for Nephrotic Syndrome Management
Goals: To partner with patient advocates, health communications experts, and medical care
providers to develop a decision support tool for children and adults with nephrotic syndrome.
PI: D. Gipson
Effort: 5%
Dates: 9/2012 –6/2015
Source: PCORI
Title: Patient Powered Research Networks (PPRN) in Nephrotic Syndrome
Goals: Develop a national research network of patients affected by nephrotic syndrome
PI: Robinson
Role: Consultant
Dates: 7/2/14-8/1/15
Effort: 5%
Source: PCORI
Title: UKIERI Trilateral Research Partnership
Goals: To develop a pediatric nephrotic syndrome registry and biobank in India, establish a joint
training program and to launch a collaborative research program between the three international
partners (India, UK and USA).
PI: Co-PIs: Bagga (India), Saleem (UK) and Gipson (USA)
Dates: 02/13 – 01/15
Effort: 2%
Source: British Council
Title: Acute Kidney Injury in the Pediatric ICU
Goals: To establish a prospective registry of all children admitted to the UM pediatric intensive
care units and evaluate the epidemiology of acute kidney injury, predictors of survival and identify
potential opportunities for interventional studies.8
PI: D Selewski
Effort: 0%
Role: Mentor
Dates: 1/2012 – 12/2013; NCE to 12/2014
Source: Renal Research Institute, LLC
Title: Vitamin D in Patients with Idiopathic Nephrotic Syndrome
Goals: To assess the prevalence of Vitamin D deficiency in children with incident nephrotic
syndrome and to determine the change in deficiency status with disease activity.
PI: D Selewski
Effort: 0%
Role: Mentor
Dates1/2011 – 12/2013; NCE to 12/2014
Source: Renal Research Institute, LLC
Title: Genzyme/Fresolimumab Clinical Trial
Goals: Clinical trial of novel agent for proteinuric patients with FSGS
PI: Site Gipson, P
Role: Co-investigator
Dates: 05/27/13 – 12/01/14
Source: CoVance Inc, Genzyme
Title: Development of a Patient Reported Outcome Measure for Adults with FSGS
Goals: The goals of this project are to gather adult patient perspective on the experience with
FSGS and then use this information to develop an initial phase patient reported outcome
measure.
PI: Site Gipson /Study S. Matthias
Dates: 05/01/2013-11/01//2013
Source: Health Outcomes Solutions
Title: Novel Therapies for Resistant Focal Segmental Glomerulosclerosis (FONT) (R21/R33)
Goals: The goal of this study is to identify novel therapeutic options for patients with multi-drug
resistant FSGS. The initial phase will include pharmacokinetic and safety evaluation of 2 novel
agents and the second phase will include a Phase II Ranking and Selection design to select the best
novel therapy option for study in a phase III clinical trial.
PI: H. Trachtman
Effort: 10%
Role: Project Co-investigator/Site PI
Dates: 3/2005 – 2/2014
Source: NIH/NIDDK (DK70341)
Title: Pediatric Trials Network: Protocol Development Team
Goals: The Pediatric Trials Network (PTN) Protocol Development Team (PDT), comprised of
experts in pediatric hypertension and clinical pharmacologists, will develop and finalize a
clinical protocol for pediatric hypertension, the PK/PD or dose-response relationship of these
medications in children and adolescents, the appropriate doses of these medications that should
be studied, and the effectiveness and comparative effectiveness of these medications in this
population.
PI: D Benjamin (Duke)
Effort: 2.5%9
Role: Co-Investigator/Steering Committee
Dates: 09/2010 – 09/2012
Source: NIH/NICHD (HHSN27500007)
Title: Pediatric Trials Network: Safety and Pharmacokinetics of Multiple Dose Lisinopril in
Pediatric Kidney Transplant Recipients
Goals: This phase I Pediatric Trials Network (PTN) study will conduct a clinical protocol for
pediatric hypertension, PK/PD and dose-response relationship of lisinopril in children and
adolescents with a stable renal allograft. The results of this trial will be incorporated into the
planned phase II study.
PI: D Benjamin (Duke)
Effort: 2.5%
Role - Co-Investigator/Site PI
Dates: 09/2011 – 08/21/2013
Source: NIH/NICHD (HHSN- 275201000003I)
Title: Michigan Institute for Clinical and Health Research (CTSA)
Goals: The goals of the Michigan Institute for Clinical and Health Research, UM’s CTSA award,
are to enable and enhance clinical and translational research throughout the institution. MICHR
provides infrastructure for the development and conduct of clinical and translational research
including biostatistics, bioinformatics, regulatory support, and other services; education, training,
and career development; facilities and technological cores for the conduct of research and
development of novel methodologies; community partnerships; and pilot funding.
PI: T Shanley
Effort: 25% (to 1/2013)
Role: Associate Director (through 2012)
Dates: 09/2012 – 05/2017
Source: NIH/NCATS UL1TR000433
Title: Michigan Institute for Clinical and Health Research (MICHR)
Goals: The University of Michigan Clinical and Translational Science Award, MICHR, provides
infrastructure for the development and conduct of clinical and translational research including
biostatistics, bioinformatics, regulatory support, and other services; education, training, and
career development; facilities and technological cores for the conduct of research and the
development of novel methodologies; infrastructure for developing community partnerships; and
pilot funding opportunities.
PI: Shanley
Effort: 25%
Role: Associate Director
Dates: 09/2007 – 05/2012
Source: NIH/NCRR (1 UL1RR024986)
Title: FSGS Cohort Study
Goals: Extension of observational monitoring to compare long term kidney and patient survival
among patients randomized to one of two therapeutic regimens for children and young adults
enrolled in the Clinical Trial of Focal Segmental Glomerulosclerosis in Children and Young Adults
Role: Principal Investigator
Effort: 5%
(Multiple PI: Gipson;Gassman;Trachtman;Kaskel)
Dates: 9/2010 – 8/1210
Source: NIH/NIDDK (1R56DK084993-01)
Title: National Network of Depression Centers Data and Coordinating Center
Goals: To facilitate the establishment of a research enhancing governance structure, facilitate the
design, implementation, analysis and presentations of the initial research protocols with the 16
centers within the NNDC.
PI: D. Gipson (8/2010-8/2011), C. Spino (9/2011 – 8/2012)
Effort: 10%
and S. Taylor (8/2010-8/2012)
Role: Co-PI (8/2010 – 8/2011) Moved Co-PI to C. Spino (9/2011)
Dates: 8/2010 – 7/2012
Source: National Network of Depression Centers
Title: Clinical Trial of Focal Segmental Glomerulosclerosis in Children and Young Adults.
Goals: Phase III study to compare randomized therapy of FSGS.
PI: D. Gipson
Effort ; 10%
Dates : 10/2002 – 03/2010
Source: NIH/NIDDK (UO1-DK-63455)
Title: PROMIS (Patient Reported Outcomes Measurement Information System) - Supplement
Goals: To develop a national resource for evaluation of patient reported outcomes in children.
This supplement will promote the validation of the newly developed items in chronic disease
populations including a) Chronic Kidney Disease and b) Obesity, among others.
PI: D. Dewalt
Effort: 5%
Role: Project PI for CKD and Obesity cohorts
Dates: 10/2008 – 3/2010
Source: NIH/NCRR 5U01AR052181-05
Title: UNC Clinical Translational Science Award (CTSA)
Goals: A national consortium with the goal of transforming how clinical and translational research
is conducted, ultimately enabling researchers to provide new treatments more efficiently and
quickly to patients.
PI: E. Pisano
Effort: 25%
Role: Associate Director, Child Health Core
Dates: 7/1/08 – 10/6/13 * UNC based funding
Source: NIH/NCRR 1UL1RR025747-01
Title: Functional Neuroimaging and Chronic Kidney Disease
Goals: Pilot study to assess the structural/functional correlates of memory in children with
chronic kidney disease.
PI: D Gipson
Effort: 2%
Dates: 7/2007 – 12/2010
Source: Renal Research Institute/UNC Biomedical Imaging and Analysis Center Grant
Title: Phase I/II Trial of Galactose in Patients with Resistant FSGS
Goals: The major goal of this study is to determine if oral galactose therapy will modify the FSGS
permeability factor and diminish urinary protein excretion in patients with resistant FSGS. This 11
funding will support the initial phase I/II portion of this investigation within the FONT study
network above.
PI: H. Trachtman, D. Gipson and V. Savin
Effort: 0
Role: Co-PI
Dates: 1/2010 – 1/2011
Source: NephCure Foundation/Long Island Jewish Medical Center
Title: Glomerular Disease Collaborative Network Patient Registries
Goals: This cohort forms the basis of many retrospective and prospective observational studies
and clinical trials for glomerular diseases such as FSGS, lupus nephritis, C1q nephropathy, IgA
nephropathy and antineutrophil cytoplasmic autoantibody associated glomerulonephritis.
PI: R. Falk and C.J. Jennette
Effort: 2.5%
Role: Co-Investigator
Dates: 12/1987 – 2009
Title: Cohort Study of Children with Chronic Kidney Disease (C-KID-I and C-KID-II)
Goals: Assess the risk factors for progression of chronic kidney disease in 540 children and
document the co-morbidities including cognition, cardiovascular and growth dysfunction.
Study PI: S. Furth and B. Warady
Effort: 1%
Site PI: via UNC D. Gipson
Dates: 1/2005 – 12/2009
Source: NIH/NIDDK U01-DK-66116
Title: Renal Epidemiology Training Program, University of North Carolina-Chapel Hill.
Goals: This grant promotes the training of doctoral and pre-doctoral participants in Renal
Epidemiology Methods.
PI: R. Falk
Effort: 0
Role: Training Faculty
Dates: 3/2004 – 2/2013
Source: NRSA/NIH/NIDDK (5-T32-DK007750-05)
Title: Safety and Pharmacokinetics of FG-3019 in adolescents with treatment resistant FSGS
Goals: Evaluate the safety and pharmacokinetics of a novel agent for treatment of adolescents with
active FSGS.
Site PI: D. Gipson
Effort : 1%
Dates : 1/2008 – 12/2009
Source: Fibrogen, Inc.
Title: Safety and Pharmacokinetics of GC-1008 in adults with treatment resistant FSGS
Goals: Evaluate the safety and pharmacokinetics of GC-1008 using a single dose, dose escalation
protocol in adults with treatment FSGS.
Site PI: D. Gipson
Effort : 1%
Dates: 9/2007 – 6/2009
Source: Genzyme, Inc.
Title: PEDS: Pediatric Education for Drug Safety12
Goals: The UNC Center for Education and Research on Therapeutics (CERTS) will create and
promulgate 'PEDS', a web-based curriculum in safe off-label pediatric prescription drug use for
pediatricians, family practitioners, pediatric dentists, nurse practitioners and pharmacists.
PI: S. Tolleson-Rinehart
Effort:
10%
Role: Co-Investigator/Expert Panelist
Dates: 10/2007 – 9/2008
Sponsor: State Attorneys General; Attorney General Consumer and Prescriber Education Grant
Program
Title: STARx (Successful transition to adulthood in renal disease)
Goals: Use 4 focus groups to assess the factors that contribute to transition in patients with chronic
kidney disease.
PI: M. Ferris
Effort: 5%
Dates: 9/2005 – 8/2007
Source: UNC Certs/NIH
Title: Depression and Anxiety in Children with CKD
Goals: Evaluate the prevalence of depression and anxiety in children with CKD using semi
structured interviews compared with survey instruments.
PI: D. Gipson
Effort : 5%
Dates: 9/2007 – 8/2009
Source: Renal Research Institute
Title: Sleep Disturbances in Children with Chronic Kidney Disease
Goals:
The objective of this study is to describe the prevalence of sleep disturbance
symptoms in a pediatric CKD population (dialysis and non-dialysis dependent patients) and to
assess whether these symptoms are associated with specific clinical features in this unique
population.
PI: I. Davis
Effort: 0
Role: Co-Investigator
Dates: 1/2007 – 12/2008
Sponsor: Midwestern Pediatric Nephrology Consortium
Title: Neurodevelopment in children with chronic kidney disease: A case for controls.
Goals: utilize a case control design to assess the association between severity of kidney
dysfunction and cognitive function in children when compared to healthy controls.
PI: D. Gipson
Effort : 5%
Dates: 10/2004 – 10/2006
Source: Renal Research Institute
Title: Concept Development Administrative Supplement: Novel Therapeutic Options for
Resistant Focal Segmental Glomerulosclerosis
Goals: This administrative supplement will support the development of a research proposal for
the investigation of innovative pharmacologic agents for the treatment of focal segmental
glomerulosclerosis.13
Co-PI: D. Gipson
Effort: 5%
Dates: 10/2003 – 03/2004
Source: NIDDK/NIH (UO1 DK 63455-Supplement)
Title: A randomized controlled trial of MMF in patients with IgA nephropathy
Goals: This clinical trial will compare MMF with standard therapy for the treatment of IgA
nephropathy.
Site PI: D. Gipson
Effort:
1%
PI-Study: Ron Hogg, Dallas Medical Center
Dates: 11/2003 – 07/2006
Source: Southwest Pediatric Nephrology Study Group
Title: Proteinuria, Hypertension and Adiposity Study
Goals: This study seeks to determine the relationship between microalbuminuria, hypertension and
body mass in a cohort of children with newly identified hypertension. The study is to be
conducted as the first of a series of collaborative studies conducted by the Southeast Pediatric
Nephrology Study Network.
PI: D. Gipson
Effort: 1%
Dates: 7/2003 – 6/2004
Source: National Kidney Foundation Affiliates
Title: Neurodevelopment in children with chronic kidney disease
Goals: To determine the association between severity of kidney dysfunction and cognitive
function in children
PI: D. Gipson
Effort: 3%
Dates: 10/2002 – 09/2004
Source: Renal Research Institute
Title: Pediatric Dialysis Research Program: Methods of dialysis adequacy in pediatric patients;
Determination of Dry Weight in Pediatric Dialysis Patients; Association of cognitive/executive
functions with dialysis adequacy; and Short daily hemodialysis in pediatric/young adult patients.
Goals: To conduct a multifaceted study of end-stage renal disease patients evaluating dialysis
dose, the effect of dialysis dose on cognition, and a pilot study of short daily dialysis in children
PI: D Gipson
Effort: 5%
Dates: 10/2001 – 10/2003
Source: Renal Research Institute
Title: Urinalysis findings in the ADDhealth Wave III Cohort
Goals: To document the prevalence of hematuria and proteinuria in a U.S. cohort of 19 to 26 year
olds.
PI: M Ferris
Effort: 0
Role: Co-investigator
Dates: 08/2003 – 07/2005
Source: Kidney Foundation of NC; Nutrition Research Center; UNC Pathology Dept.
14
Title: Characterization of homocysteine levels in non-diabetic nephrotic patients
PI: J. Paparello (Fellow)
Effort: 0
Role: Mentor and Co-investigator
Dates: 01/01/01 – 12/02002
Source: Kidney Foundation of NC
Title: Intravenous cyclophosphamide vs. mycophenolate mofetil for induction therapy of active
class IV nephritis in systemic lupus erythematosis
Goals: To evaluate the efficacy and toxicity of mycophenolate mofetil in comparison to the
standard therapy for the treatment of lupus nephritis
PI: M.A. Dooley
Effort: 1%
Role: Co-investigator
Dates: 02/2000 – 08/2002
Source: Food and Drug Administration
Title: Quality of Life Among Children with Chronic Renal Insufficiency
Goals: To determine the association between health related quality of like and degree of chronic
renal insufficiency
PI: D. Gipson
Effort: 2%
Dates: 01/2000 – 12/2001
Source: Kidney Foundation of NC
Title: Pediatric Use of Amlodipine in the Treatment of Hypertension
Goals: Randomized placebo controlled dose ranging study of amlodipine in the treatment of
hypertension in children
PI: R. Williams
Effort: 1%
Role: Co-Principal Investigator
Dates: 7/1999 – 12/2000
Source: Pfizer Pharmaceuticals
Title: Gynecologic healthcare among women with end-stage renal disease
Goals: 1) case control study of gynecologic healthcare in women with ESRD and in healthy
controls and 2) pharmacokinetics of estradiol and medroxyprogesterone acetate in women with
ESRD vs. controls
Role: Co-investigator (PI C. Stehman-Breen)
Effort: 10% (Fellow)
Dates: 1/1998 – 1/1999
Source: Northwest Kidney Foundation
Training Program
6 T32 DK065517-07
Title: Renal Epidemiology Training Program (T32)
Goals: This training program is designed to train pediatric nephrology subspecialty residents to
prepare for a career in renal epidemiology.
PI: S. Pennathur
Role: Faculty15
Dates: 7/2004 – 6/2023
Honors and Awards/Community Activities
2020-present
West Side UMC Leadership Board, Chair
2018-present
Outreach & Missions Committee, West Side UMC
2017
Staff Parish Relations Committee, West Side UMC
1/2010 – 2012
Samaritans Counseling, Board Member and Program Committee Co-Chair
3/2009
Medical Mission, Zimbabwe Orphans Endeavor, Team Leader (Kenya)
2/2008
Who’s Who in America
1/2008
Medical Mission, Zimbabwe Orphans Endeavor, Team Leader (Zambia)
2008 – present
Best Doctors in America
1/2006 – 12/2007 Southeast Pediatric Nephrology Network, Research Committee
7/2006 – 2019
ASPN Governance Taskforce, member; Abstract Reviewer; Research
Committee
9/2006 – 2009
American Federation for Medical Research, Institutional Representative
7/2006 – 6/2008
NKF-NC Board of Directors, Secretary
7/2006 – 6/2008
NKF-NC Medical Advisory Committee
9/2006 – 2009
NKF Kidney Learning System (KLS) Editorial Board
7/2004 – 6/2008
NKF North Carolina Board of Directors, member
7/2002 – 7/2003
Mission Team Co-Leader, New Horizons Youth Ranch, Brazil
9/2001 – 8/2008
NKF Kidney Camp physician and founding member Camp Board of
Directors
1/2007 – 2009
Orange United Methodist Church, Administrative Council
1/2000 – 12/2004
Orange United Methodist Church, Co-Chair Missions Committee,
Chapel Hill, NC
1/1998 – 12/1998
Haller Lake United Methodist Church, Member, Missions Committee,
Seattle, WA
1/1994 – 6/1995
Toppenish United Methodist Church, Co-chair Missions Committee, WA
8/1993 – 7/1995
National Health Service Corps
5/1992
Alpha Omega Alpha Honor Society
1/1989-3/1989
Readers Digest International Fellowship,
Externship at Maua Methodist Hospital, Maua, Kenya
Professional Service
Memberships
9/2006 – 2009
American Federation of Medical Research
9/1999 – present
American Society of Pediatric Nephrology
7/1999 – present
American Society of Nephrology
12/1995 – present
International Pediatric Nephrology Association
Editorial Board
7/2004 – 6/2008
Pediatric Nephrology
1/2011 – 2015
CJASN
11/2012 – 2016
BMC Nephrology
11/2017- present
JASN 16
11/2017-present
Journal of the Asian Pediatric Nephrology Association
2021-present
Glomerular Diseases
Ad Hoc Reviewer
2017-present
JASN
2/2011 – present
New England Journal of Medicine
6/2008 – present
Lancet
8/2008
Nephrology Dialysis and Transplant
3/2007 – present
International Journal of Peritoneal Dialysis
10/2007 – present CJASN
2/2004 – present
Pediatric Academic Societies, Annual Meeting Abstract Reviewer
6/2004 – 2019
American Society of Nephrology, Annual Meeting Abstract Reviewer
1/2003 – present
American Journal of Transplantation
1/2002 – present
American Journal of Kidney Disease
1/2002 – present
Journal of Pediatrics
10/1999 – present
Pediatric Nephrology
Career Development
2020
Education Professional Development, Presented by John Mahan, MD
Associate Dean, Ohio State University @ Pediatric Nephrology Division
meeting
2020-2021
Quality Improvement Methods, Kidney Research Network, Cheryl
Courtland, MD
2020
Diversity, Inclusion and Equity Training Session, Change it up! Bystander
intervention. Charmaine Ward, 1/23/2020
2019
Patient Centered Rounds, Department of Pediatrics, Summery 2019
2017
Executive Leadership Course
2017
Good Clinical Practice Guidelines Training and Certification (Ethics)
2017
Leadership Academy, participant
10/2008 – 11/2008 Mid-Career Leadership Initiative, UNC-Chapel Hill, participant
10/2007
Mentoring Workshop, UNC Department of Pediatrics
Professional Development Service
2020-2021
Junior Faculty Peer Mentoring Group, co-facilitator. UM Division of
Pediatric Nephrology
2019-2021
Faculty, Clinical Trials Academy for University of Michigan Faculty
2015, 2017, 2019
American Society of Pediatric Nephrology, Board Review Course Lecturer,
Glomerular Disease
2016, 2017
Woodson Faculty Development Program for Industry Sponsored Clinical
Trials, co-director
2015
ASN Kidney STARS Program Faculty
10/2014-11/2015
Responsible Conduct of Research for K Scholars program, co-lead
8/2008, 8/2009
UNC Pediatric Subspecialty Training Retreat, Scientific Writing and
Presentations Session co-lead with S. Hogan, PhD
Research Teaching/ Mentorship17
Teaching and mentorship for clinical research is an ongoing and highly diverse endeavor. A table
of research trainees follows:
Name
Date Position during
Training
Degree
Achieved
Research Field
Funding
Current Position
Eloise
Salmon, MD 2020 Faculty
n/a
Health care cost and
utilization;
Transplantation
Intramural Lecturer of
Pe
diatrics
Jason Lee,
MD
2020
Faculty
n/a
Nephrotic syndrome Intramural Assistant Professor
of Pediatrics
Sarah Elhadi,
MD
2020 Faculty
n/a
Global Health
n/a
Assistant Professor
of Pediatrics
Kelly
Walkovich,
MD
2020
Faculty Scholar,
Clinical Trials
Academy
n/a
Precision medicine
for rare immune
disorders
Clinical
Trials
Academy,
UM
Assistant Professor,
Hematology and
Oncology Division,
Department of
Pediatrics, UM
Andrea
Oliveria, MD,
MS
2020
Faculty Scholar,
Clinical Trials
Academy
n/a
Impact of pregnancy
on kidney disease
outcomes
Clinical
Trials
Academy,
UM
Lecturer, Internal
Medicine
Nephrology,
Nephrology.
Clare Lindner,
MD
2019-
2020
Lecturer,
Pediatric
Nephology
n/a
Ethics in neonatal
ESRD
n/a
Lecturer, Pediatric
Nephology,
University of MI
Brooke
Blazius, MD
2019-
2020
Nephrology
Fellow
n/a
eGFR reporting in
pediatric CKD
n/a
Nephrology Fellow,
University of MI
Jennifer Lai
Yee, MD
2019-
2020
Nephrology
Fellow; faculty n/a
Genetics and
nephrotic syndrome T32
Nephrology Fellow;
Lecturer, University
of MI
Marchel,
Dorota
07/201
8 –
06/202
1
Nephrology
Fellow
n/a
Hematuria in
Glomerular Disease n/a
Nephrology Fellow,
University of MI
Zhong, Xuhui 12/16
-
12/17
Visiting
Professor
n/a
Clinical Resource in
IgA Nephropathy in
Children
China
Scholarship
Council
Associate Professor
Peking University
First Hospital
Zubin Modi,
MD
7/15
–
6/2018;
9/19-
Nephrology
Fellow; Faculty n/a
Health Services and
Health Policy in
Chronic Kidney
Disease
Murphy
Research
award; KL2
Lecturer, Pediatric
Nephrology,
University o
f
Michigan
Justine Bunka,
MD
8/15/20
15 –
8/16
Nephrology
Fellow
n/a
Patient Education
Murphy
Research
Award
Pediatrician
Mariam
Abdulghani
6/16-
7/16
O’Brien
Summer
MD©
STOP Trial
NIH/NIDD
K
Medical Student
University of
Michigan 18
Research
Student
Grace Tsai
6/15 –
8/15
O’Brien
Summer
Research
Student
MD©
Developing a
Computable
Phenotype for
Nephrotic Syndrome
NIH/NIDD
K
Medical Resident
Vohram,
Ashima
6/1/14-
7/31/14
O’Brien
Summer
Research
Student
MD©
Chronic Kidney
Disease
NIH/NIDD
K
Medical Student,
Wayne State
University
Matthew
Sampson, MD
7/1/12 -
2019
Pediatric
Nephrology
Instructor –
Assistant
Professor
n/a
Genomics in Kidney
Disease
K08
Associate Professor,
Pediatric
Nephrology, Boston
Children’s Hospital
Rebecca
Lombel, MD
7/1/201
1-2014
Pediatric
Nephrology
Subspecialty
Fellow
Completio
n,
Pediatric
Nephrolo
gy
Fellowshi
p
Acute Kidney Injury T32
Assistant Professor,
Pediatric
Nephrology
Clinical Service
Chief, University of
Michigan
Brett Ehrmann 7/1/201
1-
Medical Student
MCE,
Pending
MD
Healt
hcare
Utilization in
Hypertensive
Children
Intramural
Internal Medicine
Resident, New York
Presbyterian
Hospital
Cheryl Tran,
MD
7/1/201
0-
Pediatric
Nephrology
Subspecialty
Fellow
Nephrotic syndrome
health care
utilization
T32
Assistant Professor,
Mayo Clinic
Marie Tanzer,
MD
7/1/201
0-
Pediatric
Nephrology
Subspecialty
Fellow
Completio
n,
Pediatric
Nephrolo
gy
Fellowshi
p
Development and
Validation of a
Patient Educational
Toolkit
T32
Assistant Professor
Pediatric
Nephrology
Maine Medical
Partners
Pediatric Specialty
Care
David
Selewski, MD 1/2010-
Pediatric
Nephrology
Subspecialty
Fellow
MCR
Vitamin D
Deficiency in
Nephrotic Syndrome
T32, RRI
grant x 3
Associate Professor,
Pediatric
Nephrology,
Medical University
of South Carolina
Larysa
Wickman, MD 1/2010-
Pediatric
Nephrology
Subspecialty
Fellow
Completio
n,
Pediatric
Nephrolo
Translational
research in nephrotic
syndrome
T32;
NEPTUNE
Career
Director of Clinical
Research,
Department of
Pediatrics 19
gy
Fellowshi
p
Developme
nt Award
Beaumont Hospital,
Royal Oak, MI
Nathanial
MacHardy
7/2008-
9/2009
Undergraduate
Student
BS
Genetics
and
Anthropol
ogy
Practice Patterns
among Pediatric
Nephrologists
Intramural
Graduate Student,
School of Public
Health, UNC-CH
Megan
Wehmeyer
5-
12/200
8
Periodontal
Fellow
DDS
Periodontal disease
and CKD: the
impact of
inflammation
K30
Assistant Professor,
University of Texas,
Houston
Rachel Kitson,
MS(c)
7/2007-
6/2008
Graduate
Student,
Psychology
PhD
Depression and
Anxiety in CKD
Renal
Research
Institute
Psychologist,
Private Practice
Waverly
Harrell, PhD
7/2007-
2010
Graduate
Student,
Psychology
PhD
Functional MRI and
working memory
RRI, UNC
BRIC, T32
Postdoctoral
Associate at Duke
University Medical
Center
Amy
Kuchenreuther
7/2006-
5/2009
Undergraduate
Research
Assistant
BS in
Biology
Depression and
Chronic Kidney
Disease
Renal
Research
Institute
Dental School
Student
NYU College of
Dentistry
Phil Icard,
PhD
7/2006-
6/2008
Graduate
Research
Assistant
PhD
Neurocognitive
function in children
with chronic kidney
disease, fMRI in
children with CKD
Renal
Research
Institute,
Biomedical
Research
Imaging
Center
Grant
Private Psychology
Practice
Jennifer
Slickers, MD
8/2004-
8/2007
Subspecialty
Resident in
Pediatric
Nephrology
MPH
1. Limitations of
Pediatric GFR
Estimating
Equations,
NHANES 2.
Environmental
factors and renal
agenesis. 3.
Cognitive Deficits in
Pediatric CKD
Research
Funding:
Renal
Research
Institute
NIH/NIDD
K T32
Pediatric
Nephrologist
Kaiser Permanente
Brian Kelly,
PharmD
7/2003-
6/2004
Pediatric
Specialty
Pharmacy
Resident
Pediatric
Pharma
cotherapy
Specialist
Cholesterol
lowering therapy in
children with
nephrotic syndrome
Hospital/Sc
hool of
Pharmacy
Clinical Assistant
Professor, Shands
Univ. Hospital,
Gainesville, FL 20
Carla Nester,
MD
7/2003
–
6/2007
Subspecialty
Resident in
Pediatric and
Internal
Medicine
Nephrology/
Epidemiology
Training
Program
Certificati
on,
Pediatric
and
Internal
Medicine
Nephrolo
gy
Genetic Basis of
Vasculitis
NIH/NIDD
K, T32
NKF-NC
Associate Prof.in
Pediatric and
Internal Medicine
Nephrology, Chief
Pediatric
Nephrology, U of
Iowa.
David
Shoham,
PhD MSPH
7/2003-
6/2005
Graduate
Student (PhD
candidate)
PhD
SES and renal
transplant survival
NIH/NIDD
K T32
Epidemiolo
gy Training
Grant
Associate Professor,
Epidemiology,
Chicago, IL
Pete Duquette,
PhD
7/2002-
6/ 2008
Graduate
Research
Assistant
PhD
Cognitive function
in children with
Chronic Kidney
Disease
Renal
Research
Institute
Psychologist,
Private Practice
Jay Paparello,
MD
7/2002
–
6/2003
Nephrology
Subspecialty
Resident
Certificati
on,
Interna
l
Medicine
Nephrolo
gy
Homocysteine in
Nephrotic Syndrome
National
Kidney
Foundation
NC
Associate Professor,
Northwestern Univ.
Crista
Wetherington,
PhD
9/2002
-
6/2005
Graduate
Student
PhD
Neurocognitive
Function of Children
and Adolescents
with Renal
Dysfunction
Renal
Research
Institute
Assistant Professor,
Training Program
Director,
Southwestern
Medical Center
Kurt
Stellwagen,
PhD
9/2002-
5/2004
Graduate
Student
PhD
Cognitive function
in children with
Chronic Kidney
Disease
Renal
Research
Institute
Assistant Professor,
Eastern Washington
University
Keisha Gibson
(Rowe), MD
7/00–
6/01;
7/05-
6/08
Pre-Doctoral;
Pediatric
Nephrology
Fellow
MD,
MPH
ANCA Vasculitis in
Children and FSGS
in Children; FSGS
Lupus Nephritis in
Children and Adults
NIH
T32 Renal
Epidemiolo
gy Training
Grant
Associate Professor,
UNC-CH
Training Program
Director, Chief,
Division of
Pediatric
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| 日期 | 时间 | 会场 | Session | 角色 | 讲题 |
|---|---|---|---|---|---|
| 2021-12-12 | 09:40-10:00 | 肾脏专场 Nephrology |
肾脏专场-上午 Nephrology（a.m.） |
讲者 Speaker | 儿童肾病综合征的治疗进展Therapeutic Approach to Nephrotic Syndrome in Childhood |
| 2021-12-12 | 10:40-10:55 | 肾脏专场 Nephrology |
肾脏专场-上午 Nephrology（a.m.） |
讨论 Discussant | 讨论Discussion |
美迪康会务通