第十六届亚洲儿科研究学会学术大会(ASPR2021)

Jean-Laurent Casanova

单位：

The Rockefeller University, USA

简历：

Jean-Laurent Casanova received his M.D. in 1987 and his Ph.D. in 1992, after training at the

Pasteur Institute in Paris and the Ludwig Institute for Cancer Research in Lausanne. He was

appointed professor at Necker in 1999 and with Laurent Abel, cofounded the Laboratory of

Human Genetics of Infectious Diseases. He was appointed professor at Rockefeller University in

2008 and named HHMI investigator in 2014. He continues to partner with Dr. Abel, maintaining

their lab in Paris and NY.

Over the last 25 years, they discovered the first monogenic inborn errors of immunity, rare and

common, which predispose otherwise healthy individuals to a single infectious disease, including

a variety of viral, bacterial, and fungal infections. In response to the SARS-CoV2 Global

Pandemic, Dr Casanova cofounded the COVID Human Genetic Effort with Helen Su at the

NIAID. He discovered monogenic inborn errors of type I interferon immunity underlying severe

forms of COVID-19 in previously healthy individuals. This led to his discovery that pre-existing

autoantibodies to type I interferons account for at least 10% of severe cases.

Dr. Casanova was recipient of multiple international awards, including the Dautrebande Prize

(Belgium, 2004), Richard Lounsbery Award (USA/France, 2008), E. Mead Johnson Award

(USA, 2010), InBev Baillet-Latour Health Prize (Belgium, 2011), Ilse and Helmut Wachter

Foundation Award (Austria, 2012), Milstein Award (USA, 2012), Robert Koch Award

(Germany, 2014), Sanofi-Institut Pasteur Award (France, 2014), Stanley J. Korsmeyer Award

(USA, 2016), and Inserm Grand Prix (France, 2016). He was elected to EMBO (2005), USA

National Academy of Sciences (2015), USA National Academy of Medicine (2015), and Royal

Academy of Medicine of Belgium (2021)

讲座视频：0

论文摘要：1

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日期	时间	会场	Session	角色	讲题
2021-12-11	11:00-11:20	免疫专场 Immunology	免疫专场-上午 Immunology (a.m.)	讲者 Speaker	重症新冠的遗传与免疫病因Genetic and immunological causes of life-threatening COVID-19
2021-12-11	11:40-11:55	免疫专场 Immunology	免疫专场-上午 Immunology (a.m.)	讨论 Discussant	讨论Discussion