Dr Simon Lam is currently working as Professor at the Department of Paediatrics and Assistant Dean (Education) of the Faculty of Medicine, The Chinese University of Hong Kong.  He practices as a paediatrician mainly in the neonatal unit at the Prince of Wales Hospital and his research interests are in neonatology, sleep/wake patterns in young children and environmental impact on child health. He is currently on the Advisory Council of the Australian New Zealand Neonatal Network and is the Honorary Treasurer of the Hong Kong College of Paediatricians.

<Education and training>

BA (Cantab), MBBChir (Cantab), MA (Cantab), MD (CUHK)

DCH (HK), DCH (International), MRCPCH (UK), FHKCPaed, FHKAM(Paed), FRCPCH

<Career History>

· Assistant Dean, Faculty of Medicine, CUHK, HK (Sep’19 – present)

· Professor, Department of Paediatrics, CUHK, HK (Aug ’20 – present)

· Associate Professor, Department of Paediatrics, CUHK, HK (Aug ’11 –Jul ‘20)

· Assistant Professor, Department of Paediatrics, CUHK, HK (Jun ‘08 – Jul ‘11)

· Resident Specialist, Department of Paediatrics, PWH, HK (Jul ‘07 – Jun ‘08)

· Resident, Department of Paediatrics, Prince of Wales Hospital, HK (Jul ‘01 – Jun ‘07)

<Selected publications>

· Wang J, Li AM, Lam HS, Leung GM, Schooling CM. Sleep Duration and Adiposity in Children and Adults: Observational and Mendelian Randomization Studies. Obesity (Silver Spring). 2019;27(6):1013–1022.

· Ng PC, Chan KYY, Yuen TP, Sit T, Lam HS, Leung KT, Wong RPO, Chan LCN, Pang YLI, Cheung HM, Chu WCW, Li K. Plasma miR-1290 Is a Novel and Specific Biomarker for Early Diagnosis of Necrotizing Enterocolitis-Biomarker Discovery with Prospective Cohort Evaluation. J Pediatr. 2019 Feb;205:83-90.e10. doi: 10.1016/j.jpeds.2018.09.031. Epub 2018 Oct 24.

· Wu YZ, Chan KYY, Leung KT, Lam HS, Tam YH, Lee KH, Li K, Ng PC. Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis. FASEB J. 2019 Jan 9:fj201801470R. doi: 10.1096/fj.201801470R. [Epub ahead of print]

· Chan PHY, Chan MHM, Li AM, Cheung RCK, Yu XT, Lam HS. Methylmercury levels in commonly consumed fish and methylmercury exposure of children and women of childbearing age in Hong Kong, a high fish consumption community. Environ Res. 2018 Oct;166:418-426. doi: 10.1016/j.envres.2018.06.033. Epub 2018 Jun 22.

· Yu XT, Sadeh A, Lam HS, Mindell JA, Li AM. Parental behaviors and sleep/wake patterns of infants and toddlers in Hong Kong, China. World J Pediatr. 2017 Oct;13(5):496-502. doi: 10.1007/s12519-017-0025-6. Epub 2017 Mar 22.

Lam HS, Chan KY, Ip M, Leung KT, Lo NW, Wong RP, Li K, Ng PC. Rapid Identification of Bacterial Antibiotic Resistance by qPCR in Infants with Gram-Negative Septicaemia: A Proof-of-Concept Study. Neonatology. 2017;111(2):145-152.

· Leung KT, Lam HS, Chan KY, Sit T, Wong RP, Yu JW, Li K, Ng PC. Regulation of Circulating Hematopoietic Stem/Progenitor Cells in Preterm Infants with Septicemia. Stem Cells Dev. 2016 Oct 4.

· Hui LL, Lam HS, Lau EY, Nelson EA, Wong TW, Fielding R. Prenatal dioxin exposure and neurocognitive development in Hong Kong 11-year-old children. Environ Res. 2016 Oct;150:205-12. doi: 10.1016/j.envres.2016.06.003. Epub 2016 Jun 11.

· Lam HS, Sit T, Chau CL, Tam YH, Cheung HM, Wong SP, Ng PC. Attitudes of Parents and Health Care Workers to Major Surgery for High-Risk Preterm Infants. J Pediatr. 2016 Oct;177:78-83.e3. doi: 10.1016/j.jpeds.2016.06.071. Epub 2016 Jul 29.

· Hui LL, Chan MH, Lam HS, Chan PH, Kwok KM, Chan IH, Li AM, Fok TF. Impact of fetal and childhood mercury exposure on immune status in children. Environ Res. 2016 Jan;144(Pt A):66-72. doi: 10.1016/j.envres.2015.11.005. Epub 2015 Nov 9.

· Hui LL, Lam HS, Leung GM, Schooling CM. Late prematurity and adiposity in adolescents: Evidence from "Children of 1997" birth cohort. Obesity (Silver Spring). 2015 Nov;23(11):2309-14. doi: 10.1002/oby.21267. Epub 2015 Sep 18.

· Lam HS, Tam YH, Poon TC, Cheung HM, Yu X, Chan BP, Lee KH, Lee BS, Ng PC. A double-blind randomised controlled trial of fish oil-based versus soy-based lipid preparations in the treatment of infants with parenteral nutrition-associated cholestasis. Neonatology. 2014;105:290-6. doi: 10.1159/000358267.

· Lam HS, Cheung HM, Poon TC, Wong RP, Leung KT, Li K, Ng PC. Neutrophil CD64 for daily surveillance of systemic infection and necrotizing enterocolitis in preterm infants. Clin Chem. 2013;59:1753-60. doi: 10.1373/clinchem.2013.209536.

· Lam HS, Kwok KM, Chan PH, So HK, Li AM, Ng PC, Fok TF. Long term neurocognitive impact of low dose prenatal methylmercury exposure in Hong Kong. Environ Int. 2013;54:59-64.

· Lam HS, Ng PC, Chu WC, Wong W, Chan DF, Ho SS, Wong KT, Ahuja AT, Li CK. Renal screening in children after exposure to low dose melamine in Hong Kong: cross sectional study. BMJ. 2008;337:a2991. doi: 10.1136/bmj.a2991.

· Lam HS, Ng PC. Biochemical markers of neonatal sepsis. Pathology. 2008 Feb;40(2):141-8.

· Fok TF, Lam HS, Ng PC, Yip AS, Sin NC, Chan IH, Gu GJ, So HK, Wong EM, Lam CW. Fetal methylmercury exposure as measured by cord blood mercury concentrations in a mother-infant cohort in Hong Kong. Environ Int. 2007;33:84-92.

<Selected grants>

Funding source: RGC Collaborative Research Fund, study period 01/06/2020 to 31/05/2023

Study title: Using Advanced Neuroimaging to Predict Language and Cognitive Outcomes in Pre-Term Infants

Reference number: C4055-19G

Amount awarded: HK$ 5,559,743, external competitive

Capacity: Co-Principal Investigator

Funding source: Food and Health Bureau - Health Care Promotion Scheme, study period 01/05/2018 to 30/04/2020

Study title: Implementation of a parent-led, healthcare professional mediated early developmental training programme for preterm children

Reference number: 01170788

Capacity: Principal Investigator

Funding source: Innovation and Technology Fund, study period 1/10/2017 to 30/09/2019

Study title: Umbilical cord blood mononuclear cell bank in Hong Kong and treatment of neonatal cerebral ischemia and anaemia

Reference number: ITS/208/16FX

Capacity: Co-Investigator

Funding source: RGC General Research Fund, study period 01/01/2016 to 30/06/2018

Study title: A prospective cohort study on fecal miR-223 and miR-451 as non-invasive biomarkers for surveillance and early diagnosis of necrotizing enterocolitis in preterm infants

Reference number: 14106715

Capacity: Principal Investigator

Funding source: RGC General Research Fund, study period 01/11/2014 to 31/1/2017

Study title: Associations between sleep/wake patterns and neurocognitive outcomes in Hong Kong Chinese preschoolers

Reference number: 14108114

Capacity: Principal Investigator

Funding source: Food and Health Bureau - Health Medical Research Fund, study period 01/02/2014 to 31/7/2015

Circulating Hematopoietic Stem/Progenitor Cells and Stem Cell-mobilizing Cytokines in Preterm Infants and Regulation during Late-onset Systemic Bacterial Infection

Reference number: 01120826

Capacity: Co-Investigator. Collaborated in study design and patient recruitment.

Funding source: RGC General Research Fund, study period 01/01/2012 to 30/06/2014

Study title: Factors affecting mercury concentration in commercially available seafood in Hong Kong

Ref no.: CUHK468111

Capacity: Principal Investigator

Funding source: Food and Health Bureau - Health and Medical Research Fund, study period 01/03/2014 to 30/08/2016

Study title: Characterisation of Benefit : Risk Ratios of Seafood Items Commonly Consumed by High-Risk Populations in Hong Kong

Reference number : 11120641

Capacity: Principal Investigator

Funding source: Food and Health Bureau - Health and Medical Research Fund, study period 01/01/2014 to 31/03/2015

Study title: Identification of Genetic Susceptibilities to Low-dose Mercury Exposure in Children

Reference number: 11120601

Capacity: Principal Investigator