Present academic & work position.
Chair of Thai Pediatric Critical Care training program
Director of CU Pediatric Critical Care training program
Chair of CU-ECMO committee
Member of board of CU Critical Care Excellence Center
Member of board of CU Critical Care Committee
Member of board of CU Ethical Committee
Member of board of Thai Critical Care Society.
Member of board of Thai Pediatric Pulmonary & Critical Care Society.
Member of American Thoracic Society
Chief of PICU
Professor of Pediatrics, (Since May 2013)
Pediatric Pulmonary & Critical Care attending
Faculty of Medicine, Chulalongkorn University
Area of research Interest
Basic science and clinical trial related to viral respiratory tract infection; especially RSV
or new emerging respiratory virus
pARDS/High frequency oscillator ventilation/ECMO
Sepsis/septic shock/Hemodynamic resuscitation & Monitoring
Therapeutic hypothermia
Infection control in PICU/VAP
Asthma treatment.
Pediatric CPR/ Pediatric Critical Care Nutrition
Education
Chulalongkorn University Hospital (1985-1991)
Bangkok, Thailand
Doctor of Medicine
Jersey City Medical Center (1992-1995)
Seton Hall University
Jersey City, NJ
Housestaff in Pediatrics
Jersey City Medical Center (1994-1995)
Jersey City, NJ.
Chief Resident, Selected
Memorial Miller Children’s Hospital of Long Beach (1995-1998)
University of California, Irvine
Irvine, CA
Pediatric Pulmonary Fellow.
Loma Linda Children’s Hospital (1999-2000)
Loma Linda University
Loma Linda, CA
Pediatric Critical Care Fellow
Medical Diploma
Diplomate American Board of Pediatrics
Diplomate American Board of Pediatric Pulmonary
Certificate in Pediatric Critical Care
WORK HISTORY
Clinical Instructor/ Attending staff (1999-present)
Acting Chief of PICU
Division of Pediatric Critical Care
Department of Pediatrics
King Chulalongkorn Memorial Hospital
Faculty of Medicine, Chulalongkorn University
Bangkok, Thailand
Rujipat. S CV 2021 pg. 2Rujipat. S CV 2021 pg. 3
Participate in a clinically based program covering all phases of Pediatric
pulmonology, including flexible fiberoptic laryngoscopy/bronchoscopy,
interpreting pulmonary function test and sleep study as well as consultation.
Responsible for Pediatric Intensive Care Unit approximately 4 months/year.
Supervise fellow and housestaff in PICU during their clinical clerkships.
Responsible for research and project from the preparation of research protocols
for submission to the research Committee to the actual performance of the
research, and the writing as well as submission of the abstracts and
manuscripts. In addition, responsible for supervising Pediatric Pulmonary
fellow research project.
Supervise and teach fellows, house staffs as well as medical students on
clinical clerkships.(Pediatric pulmonary & Critical Care)
LICENSES
California, # A054196, 1995-present/Thailand, #16932, 1991-present
Recent Research Grants:
• pARDS- RatchadaPisek Sompotch Fund, Chulalongkorn University
• pSEPSIS and Protein C Thailand Research Fund
• Epidemiology of Pediatric sepsis in Thailand, National Research Council of
Thailand
• Epidemiology of Pediatric sepsis in three Asian countries, Royal College of Thai
Pediatrician
• HFOV-Prospect trial site investigator- NIH
International research network
•
2016 Join Singapore research clinical institute (SCRI) under PACCMAN
research group
•
Epidemiology of Pediatric sepsis in ASIA
•
International multicenter research network; Prospect network HFOV and
prone position in severe pediatric ARDS ; (NIH grant.) 2018
•
International multicenter research network; Pediatric CPR: Prospective
Observational study ; (NIH grant with Children hospital of Philadelphia)2018Select International Guest Speaker
PUBLICATIONS:
Abstract & Presentations.
1. Beharry K, Samransamruajkit R, Modanlou DH “Continuous infusion of
therapeutic dosage of morphine sulfate causes up-regulation of Endothelin-1
mRNA expression in the brain stem of newborn piglets. Presented in part at
Society of Pediatric research meeting, Washington DC, 1997
2. Samransamruajkit R, Chin TW, Nussbaum E The modulation of potent
inflammatory cytokines, interleukin-6 and interleukin-8 by glucocorticoids and
ribavirin after exposure to RSV. AJRCCM 1998;157:A287
3. Samransamruajkit R, Chin WT, Nussbaum E. The modulation of potent
inflammatory cytokines, interleukin-6 and interleukin-8 by glucocorticoids and
ribavirin after exposure to RSV. Abstract in supplement to AJRCCM
1998;157:A287
4. Samransamruajkit R, Lekhanont P, Sritippayawan S, Prapphal N,
Deelodejanawong J, Bhattarakosol P, Poovorawan Y The occurrence and clinical
presentations of RSV subtype in acute bronchiolitis and viral pneumonia among
hospitalized infants and young children abstr in 11th Asian congress of pediatrics
2003;page 178-179.
5. Jitchaiwat S, Samransamruajkit R, Trinavarat P, Deelodejanawong J,
Sritippayawan S, Prapphal N. Ventilator associated pneumonia:Incidence, risk
factors, microbiology and outcome experienced from Tertiary PICU abstr in 11th
Asian congress of pediatrics 2003;page 179
6. Lekhanont P, Samransamruajkit R, Trinavarat P, Sritippayawan S, Prapphal N,
Deelodejanawong J, Poovorawan Y. The chest radiological findings of RSV
infection among hospitalized infants and young children;Does subtype really
matters? abstr in 11th Asian congress of pediatrics 2003;page 184
7 Samransamruajkit R, Hiranrat T, Prapphal N, Sritippayawan S, Deerojanawong J,
Poovorawan Y. The levels of plasma protein C in Pediatric septic shock and the
risk of death. Am J Respir Crit Care 2005;a157
8 Samransamruajkit R, Jitchaiwat S, Panruethai Trinavarat, Prapphal N,
Sritippayawan S, Deerojanawong J Ventilator Associated Pneumonia (VAP)
caremap impact on outcome experienced from tertiary care PICU Am J Respir Crit
Care 2005;a425.
9 Sritippayawan S, Wong P, Tosukhowong P, Prapphal N, Samransamruajkit R,
Deerojanawong J. Environmental tobacco smoke exposure and RSV infection in
young children. Am J Respir Crit Care 2005;a598
10 Samransamruajkit R, Jitchaiwat S, Sritippayawan S, Deerodejanawong J, Prapphal
N Adrenal insufficiency in critically ill children with ALI/ARDS Amer J Respir
Crit Care 2006; 202 a
Rujipat. S CV 2021 pg. 411 Samransamruajkit R, Jitchaiwat S, Sritippayawan S, Deerodejanawong J, Prapphal
N Plasma Nitrate(NOx) Levela and its clinical significance in Septic shock Amer
J Respir Crit Care 2006;499a
12 Samransamruajkit R, Jitchaiwat S, Deerojanawong J, Sritippayawan S, Prapphal
N. Initial plasma interleukin-10 and nitrate levels among children with septic
shock as poor prognostic parameters. Pediatr Crit Care Med 2007;8(3):a15.
13 Deerojanawong J, Samransamruajkit R, Suphapeetiporn K, Wangsaturaka D,
Prapphal N The new assessment system of the year 4th Pediatrics rotation at
chulalongkorn medical school: the correlations of the seven instruments. AMEA
2007
14 Samransamruajkit R, Heiranrat T, Chieocharnsin S, Sritippayawan S,
Deerojanawong J, Prapphal N, Poovorawan Y. The prevalence and clinical
presentations of newly human BOCA virus(hBoV) among children hospitalized
with community acquired pneumonia 5th WSPID 2007
15 Trisorus T, Samransamruajkit R, Sritippayawan S, Deerojanawong J, Prapphal N
Treatment of PDR-VAP with high dose carbapenem and ampicillin-sulbactam.
5
th WSPID 2007
16 Samransamruajkit R, Heiranrat T, Chieocharnsin S, Sritippayawan S,
Deerojawong J, Prapphal N, Poovorawan Y.The clinical impact of Influenza
among children admitted with community acquired pneumonia. 5th WSPID 2007
17 Samransamruajkit R, Heiranrat T, Chieocharnsin S, Sritippayawan S,
Deerojawong J, Prapphal N, Poovorawan Y. The prevalence, complications and
cost of hospitalization among children admitted with Influenza pneumonia in
Thailand. CIPP VIII 8th International congress on Pediatric Pulmonology. (Nice,
France)
18 Jirapaiboonsuk S, Samransamruajkit R, Tantiviwat S, Deerojanawong J,
Sritippayawan S, Prapphal N. Effect of frequency of ventilator circuit change (3
days VS 7 days) on the rate of VAP in PICU. Amer J Respir Crit Care 2008(abst,
Toronto, Canada)
19 Samransamruajkit R, Jiraratanavong K, et al The use of high frequency oscillator
ventilation (HFOV) in Pediatric ARDS with open lung technique. Abst Amer j
Respir Crit Care 2009. (San Diego, CA)
20 Samransamruajkit R, Tongnuan C, et al Pulmonary coagulopathy in Pediatric
ALI/ARDS. ESICM 2009. (Vienna)
21 Samransamruajkit R, et al Microbiology, antibiotics utilization and clinical
outcomes of VAP in Tertiary Care PICU. ESICM 2009.
22 Samransamruajkit R, et al Clinical, Functional outcome and Quality of life in
children surviving from ARDS. CHEST 2010 (Vancouver, Canada)
23 Samransamruajkit R, et al Fluids and Medications usage in children admitted with
severe sepsis/Septic shock. CHEST 2010 (Vancouver, Canada)
24 Samransamruajkit R, Jiraratanavong K, et al POTENT INFLAMMATORY
CYTOKINES RESPONSE FOLLOWING LUNG VOLUME RECRUITMENT
MANEUVERS WITH HFOV IN PEDIATRIC ARDS. PCCM 2011, Sydney, Australia.
25 Samransamruajkit R, Uppala R, Pongsanon K, et al Clinical outcomes after utilizing
SSC guideline in children with septic shock. 2012 ATS Conference San Francisco, CA,
USA
Rujipat. S CV 2021 pg. 526 Samransamruajkit R, Nakornchai K, Pongsanon K, et al Interleukin-10
Polymorphisms and Clinical risk factors in children with Severe Sepsis & Septic
shock Annual Crit Care conference, Manchester, UK 2013
27 Thongnual C, Hantragool S, Samransamriatkit R. Efficacy of non-invasive cardiac
monitoring (Ultrasonic Cardiac Output Monitor) guide in management of fluid
refractory pediatric septic shock. Pediatric Respiratory and Critical Care Medicine
Association, Annual Scientific Meeting. 2016; proceedings.
28 Samransamruajkit R, Limprayoon K, Lertbunrian R, Uppala R, Samathakanee C,
Jetanachai P, Thamsiri N CLINICAL EFFECTIVENESS OF THE UTILIZATION OF
BUNDLED CARE FOR SEVERE SEPSIS AND SEPTIC SHOCK IN THAI
CHILDREN: A MULTICENTER TRIAL WSPCCM 2016, Toronto, Canada.
29 Samransamruajkit R, et al Clinical risk factors and outcomes after a modified
EGDT in Ped Septic shock ATS Annual Meeting, San Franscisco, USA, 2016
30 Samransamruajkit R, The Epidemiology of Pediatric sepsis in three Asian
countries, oral presentation at ESPNIC 2019 Salzburg, Austria
Publications
1 Puvabuditsin S, Samransamruajkit R, Garow E, Lopez L : Postnatal
intussusception in a Premature infant, causing Jejunal Atresia, J of Pediatr
surg;1996:31:711-712
2 Puvabuditsin S, Garrow E, Samransamruajkit R et al “Epidermolysis Bullosa
Associated with congenital localized absence of skin, fetal abdominal mass, and
pyloric atresia. Pediatr Derm 1997;14:359-362
3 Samransamruajkit R, Gollapudi S, Kim CH, Gupta S, Nussbaum E Modulation of
endothelin-1 expression on pulmonary epithelia cell line(A549) after exposure to
RSV. Int J Mol Med 2000:Jul;6(1):101-5.
4 Samransamruajkit R, Moonviriyakit K, Vanapongtipagorn et al Plasma
endothelin-1 in infants and young children with acute bronchiolitis and viral
pneumonia. Asian Pac J Allergy Immunol 2002:20:229-34.
5 Chongsrisawat V, Chatchatee P, Samransamruajkit R, et al Plasma endothelin-1
levels in patients with biliary atresia:possible role in development of portal
hypertension. Pediatr Surg 2003:19; 478-81.
6 Thanasugarn W, Samransamruajkit R, Vanapongtipagorn P, et al Human
metapneumovirus infection in Thai children. Scand J Infect Dis 2003;35;754-6.
7. Samransamruajkit R, Chin TW, Yuensrigul A, et al Possible effect of chest
physical therapy in hospitalized asthmatic children. Pediatr Asthma, Allerg &
Immunol 2003;16:295-303.
8. Lekkhanont P, Samransamruajkit R, Charearnrad P, Likitnukul S, Prapphal N
Epstein Barr virus infection with unusual pneumothorax: a case report Chula Med
J 2004;48:249-252.
9. Deerojanawong J, Manuyakorn W, Prapphal N, Harnruthakorn C, Sritippayawan
S, Samransamruajkit R. Randomized controlled trial of salbutamol aerosol
therapy via metered dose inhaler-spacer vs. jet nebulizer in young children with
wheezing Pediatr Pulmonol. 2005 ;39(5):466-72.
Rujipat. S CV 2021 pg. 610. Samransamruajkit R, Prapphal N, Deerojanawong, et al Plasma soluble
intercellular adhesion molecule-1(sICAM-1) in Pediatric ARDS during high
frequency oscillator ventilation: a predictor of mortality. Asian Pac J Allergy
Immunol. 2005:23; 181-8.
11. Sritippayawan S, Jitchaiwat S, Chatchatee P, Prapphal N, Deerojanawong J,
Samransamruajkit R Disseminated cytomegalovirus infection associated with
PCP in a previously normal infant. Scand J Infect Dis 2006;38(4):312-4
12. Samransamruajkit R, Thanasugarn W, Prapphal N, et al Human metapneumovirus
in infants and young children in Thailand with lower respiratory tract
infections;Molecular characteristics and clinical presentations. J Infect
2006:52;254-63.
13. Theamboonlers A, Samransamruajkit R,Thongme C, Amonsin A, Chongsrisawat
V, Poovorawan Y. Human Coronavirus Infection among Children with Acute
Lower Respiratory Tract Infection in Thailand. Intervirology. 2006 ;50(2):71-77.
14. Wachirapaes W, Samransamruajkit R, Deerojanawong, Sritippayawan S,
Prapphal N Validity of clinical diagnosis in isolated laryngomalacia in infants
with congenital stridor Chula Med J 2007;51:13-25.
15. Samransamruajkit R, Hiranrat T, Prapphal N, Sritippayawan S, Deerojanawong J,
Poovorawan Y. The levels of plasma protein C in early phase of Pediatric septic
shock and the risk of death. Shock 2007;28:518-23
16. Samransamruajkit R, Jitchaiwat S, Deerojanawong J, Sritippayawan S, Prapphal
N. Adrenal insufficiency in early phase of Pediatric ALI/ARDS. J Crit Care
2007;22:314-8.
17. Chieocharnsin T, Chutinimitkul S, Payungporn S, Hiranras T, Samransamruajkit
R, Theamboolers A, Poovorawan Y. Complete coding sequences and
phylogenetic analysis of human Bocavirus (HBoV) Virus Res 2007;129:54-7.
18. Chutinimitkul S, Chieocharnsin T, Payungporn S, Samransamruajkit R, Hiranras
T, Theamboolers A, Poovorawan Y Molecular characterization and phylogenetic
analysis of H1N1 and H3N2 human influenza A viruses among infants and
children in Thailand. Virus Res. 2008;132:122-31.
19. Chieocharnsin T, Samransamruajkit R, Chutinimitkul S, Payungporn S, Hiranras
T, Poovorawan Y. Human bocavirus (HBoV) in Thailand: clinical manifestations
in a hospitalized pediatric patient and molecular virus characterization. J infect
2008;56:137-42.
20. Samransamruajkit R, Jitchaiwat S, Wachirapaes W, Deerojanawong J,
Sritippayawan S, Prapphal N Prevalence of Mycoplasma and Chlamydia
pneumonia in severe community acquired pneumonia among hospitalized
children in Thailand. Jpn J infect Dis. 2008;61:36-9.
21. Payungporn S, Chieochansin T, Thongme C, Samransamruajkit R, et al
Prevalence and Molecular characterization of WU/KI polyomaviruses isolated
from pediatric patients with respiratory disease in Thailand. Virus Res
2008;135:230-6.
22. Suwannakarn K, Payungporn S, Chieochansin T, Samransamruajkit R, et al
Typing (A/B) and subtyping (H1/H3/H5) of influenza A viruses by multiplex real
time RT-PCR assays. J Virol Methods. 2008;152:25-31.
Rujipat. S CV 2021 pg. 723. Payungporn S, Chieocharnsin T, Thongmee C, Panjaworayan N,
Samransamruajkit R, et al Detection and discrimination of WU/KI
polyomaviruses by real time PCR with melting curve analysis. J Virol Methods.
2008; 153:70-3.
24. Boonsak P, Payungporn S, Chieocharnsin T, Samransamruajkit R, et al Detection
of influenza virus types A& B and type A subtypes (H1, H3 & H5) by multiplex
PCR. Tohoku J Exp Med 2008;215:247-55.
25. Samransamruajkit R, Hiranrat T, et al Prevalence, clinical presentations and
complications among hospitalized children with Influenza pneumonia. Jpn J
Infect dis. 2008;61: 446-9.
26. Linsuwan P, Payungporn S, Samransamruajkit R, et al Recurrent human
rhinovirus infection in infants with refractory wheezing. Emerg Infect dis
2009;13: 506-12.
27. Linsuwan P, Payungporn S, Samransamruajkit R, et al Recurrent human
rhinovirus C infection in Thai children with acute lower respiratory tract disease. J
Infect 2009; 59: 115-21.
28. Samransamruajkit R, Jirapaiboonsuk S, et al Effect of frequency ventilator circuit
changes (3 VS 7 days) on the rate of VAP in PICU. J Crit Care 2010;25: 56-61.
29 Ruangnapa K, Samransamruajkit R, Namchaisiri J, et al The long duration of
extracorporeal membrane oxygenation in a child with acute severe hypoxic
respiratory failure treated in a resource-limited center. Perfusion 2012;27: 547-9.
30 Samransamruajkit R, Jiraratanawong K, Siritantiwat S, et al Potent inflammatory
cytokine response following lung volume recruitment maneuvers with HFOV in
Pediatric ARDS. Asian Pac J Allergy Immunol 2012;30: 197-203.
31 Samransamruajkit R, Tongnuan C, Sosothikul D, et al Pulmonary coagulopathy
in Pediatrics ALI/ARDS. Crit Care & Shock 2013:16;68-73.
32 Samransamruajkit R, Uppala R, Pongsanon K, et al Clinical outcomes after
utilizing surviving sepsis campaign in children with septic shock and prognostic
value of initial plasma NT-proBNP Indian J Crit Care Med 2014;18:70-6.
33. Samransamruajkit R, Nakornchai K, Pongsanon K, et al Interleukin-10
polymorphisms and clinical risk factors in children with severe sepsis and septic
shock. Crit Care & Shock 2014:2:50-57.
34 Samransamruajkit R, Uppala, R, Pongsanon K, et al Clinical outcomes after
utilizing surviving sepsis campaign in children with septic shock and prognostic
value of initial plasma NT-proBNP. Indian JCCM 2014 Feb;18(2):70-6.
35 Samransamruajkit R, Rassameehirun C , et al A comparison of clinical efficacy
between high frequency oscillatory ventilation and conventional ventilation with
lung volume recruitment in pediatric acute respiratory distress syndrome: A
randomized controlled trial. Indian J Crit Care Med. 2016 Feb;20(2):72-7.
36 Samransamruajkit R It Is Too Early to Say No Place for High-Frequency
Oscillatory Ventilation in Children with Respiratory Failure. Am J Respir Crit
Care Med. 2016 Aug 15;194(4):521-522.
37 Samransamruajkit R, Saelim K, Hantragool S, et al A comparison of NSS vs
balanced salt solution as a fluid resuscitation and impact of fluid balance on
clinical outcomes in pediatric septic shock Crit Care Shock (2017) 20:68-75
Rujipat. S CV 2021 pg. 838 Wong JJ1, Phan HP, Phumeetham S, Ong JSM, Chor YK, Qian S,
Samransamruajkit R, et al; Pediatric Acute & Critical Care Medicine Asian
Network (PACCMAN). Risk Stratification in Pediatric Acute Respiratory Distress
Syndrome: A Multicenter Observational Study. Crit Care Med 2017
Nov;45(11):1820-1828.
39 Sitthikarnkha P, Samransamruajkit R, et al High-Flow Nasal Cannula versus
Conventional Oxygen Therapy in Children with Respiratory Distress. Indian J
Crit Care Med. 2018 May;22(5):321-325
40 Gan CS, Wong JJ, Samransamruajkit R, et al Pediatric Acute and Critical Care
Medicine Asian Network (PACCMAN). Differences Between Pulmonary and
Extrapulmonary Pediatric Acute Respiratory Distress Syndrome: A Multicenter
Analysis.Pediatr Crit Care Med. 2018 Oct;19(10):e504-e513
41 Prajongkit T, Veeravigrom M, Samransamruajkit R. Prognostic value of
continuous electroencephalography in children undergoing therapeutic
hypothermia after cardiac arrest: A pilot study. Neurophysiol Clin. 2019
Feb;49(1):41-47
42 Samransamruajkit R, Limprayoon K, Lertbunrian R, Uppala R, Samathakanee
C, Jetanachai P, Thamsiri N. The Utilization of the Surviving Sepsis Campaign
Care Bundles in the Treatment of Pediatric Patients with Severe Sepsis or Septic
Shock in a Resource-Limited Environment: A Prospective Multicenter Trial.
Indian J Crit Care Med. 2018 Dec;22(12):846-851
43 Saetae T, Pongpirul K, Samransamruajkit R. Assessment of early goal-directed
therapy guideline adherence: Balancing clinical importance and feasibility. PLoS
One. 2019 Mar 15;14(3):e0213802
44 Wong JJ, Liu S, Dang H, Anantasit N, Phan PH, Phumeetham S, Qian S, Ong
JSM, Gan CS, Chor YK, Samransamruajkit R, Loh TF, Feng M, Lee JH The
impact of high frequency oscillatory ventilation on mortality in paediatric acute
respiratory distress syndrome. ; Pediatric Acute & Critical care Medicine Asian
Network (PACCMAN). Crit Care. 2020 Jan 31;24(1):31.
45 Lee JH, Rogers E, Chor YK, Samransamruajkit R, Koh PL, Miqdady M, Al
Mehaidib AI, Pudjiadi A, Singhi S, Mehta NM Optimal nutrition therapy in
paediatric critical care in the Asia-Pacific and Middle East: a consensus. Asia Pac
J Clin Nutr. 2016 Dec;25(4):676-696.
46 Zeng JS, Qian SY, Wong JJ, Ong JS, Gan CS, Anantasit N, Chor YK,
Samransamruajkit R, Phuc PH, Phumeetham S, Feng X, Sultana R, Loh TF, Lee
JH.Non-Invasive Ventilation in Children with Paediatric Acute Respiratory
Distress Syndrome. Ann Acad Med Singap. 2019 Jul;48(7):224-232.
47 Sirivongrangson P, Kulvichit W, Payungporn S, Pisitkun T, Chindamporn A,
Peerapornratana S, Pisitkun P, Chitcharoen S, Sawaswong V, Worasilchai N,
Kampunya S, Putcharoen O, Thawitsri T, Leelayuwatanakul N, Kongpolprom N,
Phoophiboon V, Sriprasart T, Samransamruajkit R, Tungsanga S, Tiankanon K,
Lumlertgul N, Leelahavanichkul A, Sriphojanart T, Tantawichien T, Thisyakorn
U, Chirathaworn C, Praditpornsilpa K, Tungsanga K, Eiam-Ong S, Sitprija V,
Kellum JA, Srisawat N Endotoxemia and circulating bacteriome in severe
COVID-19 patients. Intensive Care Med Exp. 2020 Dec 7;8(1):72.