2020 ~ present:
Tu R, Tang X, Xu R, Ping Z, Yu Z, Xie T. Gap junction-transported cAMP from the niche controls stem cell progeny differentiation. Proc Natl Acad Sci USA 2023; 120, (35), article number e2304168120.
Zhang S, Yang F, Huang Y, He L, Li Y, Wan YCE, Ding Y, Chan KM, Xie T, Sun H, Wang H. ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression. Nature Commun. 2023; 14(1) 4978.
Zhou Q, Zhao C, Yang Z, Qu R, Li Y, Fan Y, Tang J, Xie T, Wen Z. Cross-organ single-cell transcriptome profiling reveals macrophage and dendritic cell heterogeneity in zebrafish. Cell Rep. 2023; 42(7) 112793.
Liu W, Xie H, Liu X, Xu S, Cheng S, Wang Z, Xie T, Zhang ZC, Han J. PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation. Cell Rep. 2023; 42(3) 112277.
Pang J, Zhao X, Deng F, Tsuchiya D, Malloy S, Parmely T, Xie T, Wang Y. A freeze-substitution approach with solvent-based glyoxal fixative to prevent distortion of ocular structures. J. Histotechnol. 2022; 45(4) 172-181.
Pang J, Thomas N, Tsuchiya D, Parmely T, Yan D, Xie T, Wang Y. Step-by-step preparation of mouse eye sections for routine histology, immunofluorescence, and RNA in situ hybridization multiplexing. STAR Protoc. 2021; 2(4) 100879.
Tu R, Duan B, Song X, Chen S, Scott A, Hall K, Blanck J, DeGraffenreid D, Li H, Perera A, Haug J, Xie T. Multiple niche compartments orchestrate stepwise germline stem cell progeny differentiation. Current Biology. 2021; 31(4): 827-839.
Pang J, Le L, Zhou Y, Tu R, Hou Q, Tsuchiya D, Thomas N, Wang Y, Yu Z, Alexander R, Thexton M, Lewis B, Corbin T, Durnin M, Li H, Ashery-Padan R, Yan D, Xie T. Notch signaling controls ciliary body morphogenesis and secretion by directly regulating Nectin expression. Cell Reports. 2021; 34(2): 108603.
Tu R, Duan B, Song X, Xie T. Glypican Dlp-mediated Hedgehog and Wnt signaling interdependence is crucial in the niche for germline stem cell progeny differentiation. Science Advances. 2020; aaz0480.
Zuo F, Tu R, Duan B, Yang Z, Ping Z, Song X, Chen S, Price A, Li H, Scott A, Perera A, Li S, Xie T. Drosophila YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs. Proc Natl Acad Sci U S A. 2020; 117(7): 3603-3609.
2015 ~ 2019:
Mao Y, Tu R, Huang Y, Mao D, Yang Z, Lau PK, Ni J, Guo Y, Xie T. The exocyst functions in niche cells to promote germline stem cell progeny differentiation by directly controlling EGFR membrane trafficking. Development. 2019;146(13): dev174615.
Ma X, Zhu X, Han Y, Story B, Do T, Song X, Wang S, Zhang Y, Blanchette M, Gogol M, Malanowski K, Peak A, Anoja P, Xie T. Aubergine controls germline stem cell self-renewal and progeny differentiation via distinct mechanisms. Developmental Cell 2017; 41(2):157-169.
Ma X, Han Y, Song X, Do T, Yang Z, Ni J, Xie T. DNA damage-induced CHK2 activation compromises germline stem cell self-renewal and lineage differentiation. Development. 2016; 143(23):4312-4323.
Lu T, Wang S, Gao Y, Mao Y, Yang Z, Liu L, Song X, Ni J, Xie T. COP9-Hedgehog axis regulates the function of the germline stem cell progeny differentiation niche in the Drosophila Ovary. Development. 2015; 142(24):4242-52.
Fu Z, Geng C, Wang H, Yang Z, Weng C, Li H, Deng L, Liu L, Liu N, Ni J, Xie T. Twin promotes the maintenance and differentiation of germline stem cell lineage through modulating multiple pathways. Cell Reports. 2015; 13(7):1366-79.
Wang S, Gao Y, Song X, Ma X, Zhu X, Mao Y, Yang Z, Ni J, Li H, Malanowski KE, Anoja P, Park J, Haug J and Xie T. Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche. eLife. 2015; 4:e08174.
Ouyang J, Yu W, Liu J, Zhang N, Florens L, Chen J, Liu H, Washburn M, Pei D, Xie T. Cyclin-dependent kinase-mediated Sox2 phosphorylation enhances the ability of Sox2 to establish the pluripotent state. J Biol Chem. 2015; 290(37):22782-94.
2010 ~ 2014:
Pan L, Wang S, Lu T, Weng C, Song X, Park JK, Sun J, Yang ZH, Yu J, Tang H, McKearin DM, Chamovitz DA, Ni J, Xie T. Protein competition switches the function of COP9 from self-renewal to differentiation. Nature. 2014; 514(7521):233-6.
Chen S, Li H, Gaudenz K, Paulson A, Guo F, Trimble R, Peak A, Seidel C, Deng C, Furuta Y, Xie T. Defective FGF signaling causes coloboma formation and disrupts retinal neurogenesis. Cell Res. 2013; 23(2):254-73.
Zhou Y, Tanzie C, Yan Z, Chen S, Duncan M, Gaudenz K, Li H, Seidel C, Lewis B, Moran A, Libby RT, Kiernan AE, Xie T. Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye. Proc Natl Acad Sci U S A. 2013; 110: 8966-71.
Li T, Lewallen M, Chen S, Yu W, Zhang N, Xie T. Multipotent stem cells isolated from the adult mouse retina are capable of producing functional photoreceptor cells. Cell Res. 2013; 23(6):788-802.
Kirilly D, Wang S, Xie T. Self-maintained escort cells form a germline stem cell differentiation niche. Development. 2011; 138:5087-5097.
Wang X, Pan L, Wang S, Zhou J, McDowell W, Park J, Haug J, Staehling K, Tang H, Xie T. Histone H3K9 Trimethylase Eggless Controls Germline Stem Cell Maintenance and Differentiation. PLoS Genet. 2011; 7:e1002426.
Chen S, Kaneko S, Ma X, Chen X, Ip YT, Xu L, Xie T. Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion. Proc Natl Acad Sci U S A. 2010; 107:19939-19944.
2005 ~ 2009:
Shen R, Weng C, Yu J, Xie T. eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary. Proc Natl Acad Sci U S A. 2009; 106:11623-11628.
Shen R, Xie T. Stem cell self-renewal versus differentiation: tumor suppressor Mei-P26 and miRNAs control the balance. Cell Res. 2008; 18:713-715.
Jin Z, Kirilly D, Weng C, Kawase E, Smith S, Schwartz J, Xie T. Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary. Cell Stem Cell. 2008; 2:39-49.
Song X, Call GB, Kirilly D, Xie T. Notch signaling controls germline stem cell niche formation in the Drosophila ovary. Development. 2007; 134:1071-1080.
Pan L, Chen S, Weng C, Call G, Zhu D, Tang H, Zhang N, Xie T. Stem cell aging is controlled both intrinsically and extrinsically in the Drosophila ovary. Cell Stem Cell. 2007; 1:458-469.
Jin Z, Xie T. Dcr-1 maintains Drosophila ovarian stem cells. Curr Biol. 2007; 17:539-544.
Xi R, Xie T. Stem cell self-renewal controlled by chromatin remodeling factors. Science. 2005; 310:1487-1489.
Xi R, Doan C, Liu D, Xie T. Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway. Development. 2005; 132:5365-5374.
Kirilly D, Spana EP, Perrimon N, Padgett RW, Xie T. BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary. Dev Cell. 2005; 9:651-662.
1994 ~ 2004:
Song X, Wong MD, Kawase E, Xi R, Ding BC, McCarthy JJ, Xie T. Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary. Development. 2004; 131:1353-1364.
Kawase E, Wong MD, Ding BC, Xie T. Gbb/Bmp signaling is essential for maintaining germline stem cells and for repressing bam transcription in the Drosophila testis. Development. 2004; 131:1365-1375.
Zhu CH, Xie T. Clonal expansion of ovarian germline stem cells during niche formation in Drosophila. Development. 2003; 130:2579-2588.
Song X, Xie T. Wingless signaling regulates the maintenance of ovarian somatic stem cells in Drosophila. Development. 2003; 130:3259-3268.
Song X, Zhu CH, Doan C, Xie T. Germline stem cells anchored by adherens junctions in the Drosophila ovary niches. Science. 2002; 296:1855-1857.
Song X, Xie T. DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary. Proc Natl Acad Sci USA. 2002; 99:14813-14818.
Xie T, Spradling AC. A niche maintaining germ line stem cells in the Drosophila Ovary. Science. 2000; 290:328-330.
Xie T, Spradling AC. decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell. 1998; 94:251-260.
Xie T, Finelli AL, Padgett RW. The Drosophila saxophone gene: a serine-threonine kinase receptor of TGF-b superfamily. Science. 1994; 263:1756-1759.
