第十二届临床药学湘雅国际论坛

首页临床精准用药相关研究成果

欢迎辞大会信息会议日程参会注册照片直播大会直播交通指南防疫须知论文集药物性损伤相关研究成果临床精准用药相关研究成果

临床精准用药相关研究成果

一、抗精神药物精准用药

1. Diminished treatment response in relapsed versus first-episode schizophrenia as revealed by a panel of blood-based biomarkers: A combined cross-sectional and longitudinal study，蔡骅琳，张毕奎等

2. Therapeutic efficacy of atypical antipsychotic drugs by targeting multiple stress-related metabolic pathways，蔡骅琳，李焕德等

3. Reduced erythrocyte membrane polyunsaturated fatty acid levels indicate diminished treatment response in patients with multi- versus first-episode schizophrenia，蔡骅琳等

4. Disturbance of neurotransmitter metabolism in drug‑naïve, first‑episode major depressive disorder: a comparative study on adult and adolescent cohorts，蔡骅琳等

5. Effect of Probiotic Supplements on Oxidative Stress Biomarkers in First-Episode Bipolar Disorder Patients: A Randomized, Placebo-Controlled Trial，蔡骅琳等

6. Metabolomic Analysis of Biochemical Changes in the Plasma and Urine of First-Episode Neuroleptic-Naiv̈e Schizophrenia Patients after Treatment with Risperidone，蔡骅琳，李焕德等

二、抗菌药物精准用药

1. Population pharmacokinetics, safety and dosing optimization of voriconazole in patients with liver dysfunction: A prospective observational study，颜苗，向大雄等

2. Predictors of Voriconazole Trough Concentrations in Patients with Child–Pugh Class C Cirrhosis: A Prospective Study，颜苗等

3. Predictors of Adverse Events and Determinants of the Voriconazole Trough Concentration in Kidney Transplantation Recipients，颜苗等

4. C/MIC > 4: A Potential Instrument to Predict the Efficacy of Meropenem，颜苗等

5. Does Prolonged Infusion Time Really Improve the Efficacy of Meropenem Therapy? A Prospective Study in Critically Ill Patients，颜苗等

6. A Large Sample Retrospective Study on the Distinction of Voriconazole Concentration in Asian Patients from Different Clinical Departments，颜苗等

7. Polymyxin B-Associated Nephrotoxicity and Its Predictors: A Retrospective Study in Carbapenem-Resistant Gram-Negative Bacterial Infections，屈健等

8. Therapeutic Drug Monitoring of Ceftazidime-Avibactam Concentrations in Carbapenem-Resistant K. pneumoniae-Infected Patients With Different Kidney Statuses，屈健等

9. A Comparative Study of the Microbiological Efficacy of Polymyxin B on Different Carbapenem-Resistant Gram-Negative Bacteria Infections，屈健等

10. Polymyxin B-Based Regimens for Patients Infected with Carbapenem-Resistant Gram-Negative Bacteria: Clinical and Microbiological Efficacy, Mortality, and Safety，王颖等

11. Nephrotoxicity and Efficacy Assessment of Polymyxin B Use in Renal Transplant Patients，屈健等

12. Clinical Efficacy of Polymyxin B in Patients Infected with Carbapenem-Resistant Organisms，屈健等

13. Population pharmacokinetics and exposure-response analysis of tigecycline in patients with hospital-acquired pneumonia，周艳钢，徐萍，李焕德等

14. Population Pharmacokinetics of Polymyxin B and Dosage Optimization in Renal Transplant Patients，张毕奎，周艳钢等

15. Higher incidence of neurotoxicity and skin hyperpigmentation in renal transplant patients treated with polymyxin B，周艳钢，徐萍等

16. Pharmacokinetic/pharmacodynamic evaluation of tobramycin dosing in critically ill patients: the Hartford nomogram does not fit，李三望等

三、抗肿瘤药物精准用药

1. CircRNA Microarray Profiling Reveals hsa_circ_0058493 as a Novel Biomarker for Imatinib-Resistant CML，徐萍等

2. Construction of a Five-Super-Enhancer-Associated-Genes Prognostic Model for Osteosarcoma Patients，屈健，鲁琼等

3. Functions and Clinical Significance of Super-Enhancers in Bone-Related Diseases，鲁琼等

4. Super-enhancers: a new frontier for epigenetic modifiers in cancer chemoresistance，鲁琼，屈健等

5. An interactive nomogram based on clinical and molecular signatures to predict prognosis in multiple myeloma patients，屈健等

因时间有限，湖南省毒物咨询中心三十周年代表性论文摘选仅收录了2012-2022年期间发表的部分关于临床毒理学、药物性损伤和临床精准用药的论文，若有相关论文未被收录，敬请谅解！